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thromboplastin

thromboplastin

9.9
A lab chemical that contains tissue factor and starts a blood clotting test
  • noun
  • /ˌθrɒmboʊˈplæstɪn/
  • Specialized
translation icon : tromboplastina
  • In the laboratory, they used thromboplastin to measure the prothrombin time in patients suspected of bleeding disorders.
  • partial thromboplastin
  • activated thromboplastin
  • thromboplastin time

Examples

  • Laboratory studies revealed increased prothrombin and activated partial thromboplastin times, as well as a significant metabolic acidosis on the arterial blood gas.

    Academic text (2007)
  • In their thrombotic patients, the addition of APC to plasma did not result in the expected prolongation of the activated partial thromboplastin time (APTT).

    Academic text (1993)
  • The doctor ordered tests that required thromboplastin to evaluate the patient's coagulation status.

  • During the coagulation study, the presence of thromboplastin was crucial for initiating the extrinsic pathway.

Compounds

A protein in blood that helps it to clot and whose lack causes heavy bleeding

Surface Forms

Morphology

thromboplastin = thrombus (opaque) = thrombo + plasto + in

The laboratory reagent sense uses the same technical morphemes; the combining forms and '-in' are specialist elements not transparent to average learners.

Etymology

The word thromboplastin comes from the Greek parts thrombo- 'clot' and -plastin 'to form', and you can remember -plastin by thinking of plastic as 'shaping'. In the lab, a thromboplastin reagent is called that because it makes blood start to 'form' a 'clot', which is exactly what the test needs to measure.