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rotenone

rotenone

9.9
A chemical used in research to cause Parkinson's-like brain damage in animals
  • noun
  • /ˈroʊtəˌnoʊn/
  • Specialized
: rotenona
  • Overall, however, anesthetics are much less effective than rotenone for collecting hidden fish, which leave their hiding places (and become collectible) when they are exposed to rotenone, but usually fail to do so when anesthetized.

Examples

  • Moreover, because rotenone is thermally liable, cooking reduces the potential risk to humans who consume fish exposed to the compound.

    Academic text (2008)
  • Researchers injected a small amount of rotenone into the brain of a mouse to study its effects on Parkinson's disease.

  • Fish killed with rotenone retain very small amounts of it, mostly in inedible body parts.

    Academic text (2008)
  • However, to be effective, science and management decisions must be made on the basis of the best data available, and the best available methods for obtaining that information on marine biodiversity involve small-scale rotenone sampling.

    Academic text (2008)
  • Overall, however, anesthetics are much less effective than rotenone for collecting hidden fish, which leave their hiding places (and become collectible) when they are exposed to rotenone, but usually fail to do so when anesthetized.

    Academic text (2008)
  • Furthermore, rotenone produces more persistent disorientation in fish than do anesthetics, making the fish easier to collect (Ackerman and Bellwood 2002).

    Academic text (2008)
  • Information on the degradation of rotenone in aquatic and terrestrial environments is available from the same sources that provide information about rotenone's use as a pesticide (see above).

    Academic text (2008)
  • It is widely recognized that rotenone is chemically unstable and degrades rapidly in the environment through abiotic mechanisms (photolysis and hydrolysis).

    Academic text (2008)
  • In experiments, scientists used rotenone to induce Parkinson's disease symptoms in rats by affecting mitochondrial function.

  • The study found that exposure to rotenone caused significant changes in the animal models, mimicking the pathology of Parkinson's disease.

Surface Forms

rotenone singular
rotenones plural

Morphology

rotenone = roten + one

As a technical toxicology/neuroscience term, the apparent parts do not yield the sense for general learners; 'roten' is not an independent English word and the name functions as a specialized chemical label.

Etymology

Rotenone has the same name origin, from the plant root name roten plus the chemical ending -one, and scientists kept that name when they used the substance in labs. So when you read rotenone in research it means this plant-made chemical that researchers use to create Parkinson's-like brain damage in animal studies.