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nucleotidase

nucleotidase

1 9.9
An enzyme that breaks down the building blocks of DNA or RNA by removing phosphate groups
  • noun
  • /ˌnjuːkliˈoʊtədeɪs/
  • Specialized
: nucleotidasa
  • The liver produces nucleotidase to help process nucleotides by removing their phosphate groups during metabolism.

Examples

  • Researchers measured the activity of nucleotidase in different tissue samples.

  • A deficiency in nucleotidase can affect the breakdown of nucleotides in the body.

  • The liver produces nucleotidase to help process nucleotides during metabolism.

  • The nucleotidase enzyme plays a crucial role in DNA metabolism.

  • Many nucleotidases are involved in cellular signaling pathways.

  • Researchers measured the level of nucleotidase activity in various tissue samples to study nucleotide breakdown.

  • A deficiency in nucleotidase can lead to issues in the body's ability to break down nucleotides effectively.

Surface Forms

nucleotidase singular
nucleotidases plural

Morphology

nucleotidase = nucleotide (semi-transparent) = nucleotide + ase

The suffix '-ase' is commonly used to denote enzymes, but understanding the specific function of 'nucleotidase' requires specialized knowledge.

Etymology

Nucleotidase comes from nucle- (from nucleus) meaning 'core' or 'center', and the ending -ase, a common enzyme ending you see in words like lipase. So a nucleotidase is an enzyme that works on nucleotides, the 'core' building blocks of DNA and RNA, and helps 'break down' those molecules by removing their phosphate parts.