noninferiority
- noun
- /ˌnɒnˌɪn.fɪəˈrɪə.ti/
- Specialized
- The mean decrease in HbA1c levels was 0.83% for both groups, thereby illustrating the noninferiority of Gla-300 for glycemic control.
- noninferiority trial
- noninferiority margin
- criteria for noninferiority
Examples
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Overall, the trial by Bernard and colleagues provides strong evidence for the noninferiority of 6 weeks of antibiotics compared with 12 weeks for PVO.
Academic text (2015) -
All studies were powered to detect differences between Gla-300 and the comparator Gla-100 or to demonstrate the noninferiority of Gla-300 to Gla-100.
Academic text (2017) -
Another report described the noninferiority of evening administration of LT4, compared with that half an hour before breakfast, in drug-naive patients.
Academic text (2016) -
With an estimated treatment difference of 0.08%, the noninferiority of insulin degludec was confirmed.
Academic text (2017) -
The mean difference of 0.01% between the treatment arms met predefined criteria, thus establishing the noninferiority of Gla-300.
Academic text (2017) -
The BEGIN: Flex trial was designed to test the noninferiority of insulin degludec given at forced-flex intervals of 8 to 40 hours versus Gla-100 given once daily at the evening meal.
Academic text (2017) -
The study confirmed the noninferiority of the new treatment compared to standard care in terms of patient outcomes.
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Evidence from various trials supports the noninferiority of the shorter antibiotic course when compared to the traditional longer regimen.
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Clinical data showed the noninferiority of the drug against its competitor, making it a viable option for treatment.
Antonyms
How Inferior
Surface Forms
Morphology
noninferiority = inferiority (semi-transparent) = non + inferior + ity
The prefix 'non-' straightforwardly negates 'inferiority', but the combined term commonly has a specialized statistical/clinical meaning that goes beyond the literal negation.
Etymology
The word noninferiority starts with non- meaning 'not' and the part inferior meaning 'lower' or 'worse', so it literally means 'not lower'. That's why in medicine a noninferiority study is used to show a new treatment is 'not worse' than the standard treatment.