noncoding
1
6.6
- noun
- /nɒnˈkoʊdɪŋ/
- Specialized
:
secuencia no codificante
- The majority of the mammalian genome consists of noncoding sequences, which play crucial roles in cellular functions.
- noncoding regions
- noncoding RNA
- noncoding sequence
Examples
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Research suggests that mutations in noncoding regions of DNA may contribute to the development of certain diseases.
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"Moreover, it's possible that you won't see epigenetic changes from looking at genes—you might see it, instead, in noncoding regions in DNA."
Academic text (2013) -
"There's literally this vast open space of noncoding sequence.
Academic text (2009) -
"This is why it's important to count these noncoding genes, to classify them," Carninci says.
Academic text (2009) -
"If proteins are the skeletons of life, these noncoding RNAs could be like the decorations that make one species different from another," Guigo adds.
Academic text (2009) -
The problem remains of explaining the wide variation across the eukaryotes in the proportion of noncoding to coding DNA, even within the same genus or species.
Blog text (30) -
The group is currently focused on studying airway expression of the small noncoding RNA sequences known as microRNAs, or miRNAs, which regulate the genetic response to smoking.
Academic text (2012) -
Genetic variants associated with complex diseases largely reside in the noncoding, presumably regulatory, regions of the genome (Zhang and Lupski 2015).
Academic text (2017) -
MicroRNAs (miRNAs) are a class of small noncoding (19- to 24-nucleotide) RNAs that regulate the expression of target mRNAs at the post-transcriptional level 1, 2.
Blog text (18) -
Scientists are studying the functions of various noncoding RNA molecules in gene regulation.
Synonyms
Parts of DNA that do not make proteins and help control when genes work
Antonyms
Compounds
- Specialized
Parts of DNA that do not make proteins and help control when genes work
How Coding
Surface Forms
Morphology
noncoding = coding (transparent) = non + code + ing
Derived by prefixation non- + 'coding' (where 'coding' denotes sequences that code for proteins); the noun sense names the negated entity.
Etymology
As a noun, noncoding joins non- 'not' and coding 'giving instructions' to name a piece of DNA or RNA that does 'not' code for a protein, even though it can still have an important role.