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nephrotoxicity

nephrotoxicity

1 9.9
Damage to the kidneys caused by a harmful drug or chemical
  • noun
  • /ˌnɛfroʊtɒkˈsɪsɪti/
  • Specialized
: nefrotoxicidad
  • Due to the potential for nephrotoxicity, doctors recommended regular blood tests to track kidney health during treatment.

Examples

  • Blood pressure should also be monitored because the likelihood of nephrotoxicity is increased when there is hypertension.

    Academic text (1991)
  • Monitoring of circulating drug levels may limit renal impairment in patients on cyclosporin or aminoglycosides, although as many as 33% of cases of aminoglycoside nephrotoxicity occur in patients with "therapeutic" levels.

    Academic text (1995)
  • Unfortunately, associated oto- and nephrotoxicity limit the use of this class of drugs.

    Academic text (2008)
  • Avoidance of nephrotoxicity and further insult

    Academic text (2016)
  • Further adverse reactions were later described, namely nephrotoxicity and neuromuscular blockade.

    Academic text (1998)
  • The standard medical therapy for RCM is amphotericin B in a dose of 1.0 to 1.5 mg/kg/day for a period of several weeks to several months, depending on the clinical response and the degree of the drug's side effects, especially nephrotoxicity.

    Academic text (2004)
  • Potential for adverse effects includes hypersensitivity reaction, hypokalemia, GI disturbance, anemia, nephrotoxicity, and tachycardia.

    Academic text (2005)
  • The doctors warned that the medication might cause nephrotoxicity, so they monitored his kidney function closely.

  • In some cases, patients experienced nephrotoxicity after using certain antibiotics, highlighting the need for careful dosage.

How Harmful

renal failure
  • Specialized
12 3.9
nephrotoxicity
  • Specialized
1 9.9

Surface Forms

Morphology

nephrotoxicity = nephrotoxic (semi-transparent) = nephro + toxic + ity

Formed from the medical combining form 'nephro-' (kidney) + 'toxic' + '-ity'; 'toxic' and '-ity' are transparent but the 'nephro-' element is specialized and may be unknown to average learners.

Etymology

The word nephrotoxicity joins nephro- ('kidney') and toxicity ('poison' or 'harm'), and you can see the same idea in the familiar word toxic. So, nephrotoxicity means 'poisoning' or 'harm' to the kidneys.