Skip to main content
nephrotoxic

nephrotoxic

1 9.9
Harmful to the kidneys
  • adjective
  • /ˌnɛfroʊˈtɒksɪk/
  • Specialized
: nefrotóxico
  • Elderly patients are therefore more susceptible to the effects of nephrotoxic drugs.
  • nephrotoxic drugs

Examples

  • He had no history of kidney disease or exposure to nephrotoxic substances.

    Academic text (2006)
  • There is a potential for additive renal toxicity with other drugs that are nephrotoxic or have the potential to cause hypotension.

    Academic text (2005)
  • There were no significant differences in the number of patients who received nephrotoxic drugs during dopamine or placebo infusion.

    Academic text (2000)
  • Interestingly, aminoglycosides can be less nephrotoxic without compromising antimicrobial activity when administered once daily.

    Academic text (1995)
  • In most cases, AKI is attributable to simple causes such as volume depletion, hypotension, and exposure to nephrotoxic medications.

    Academic text (2016)
  • For patients at increased risk of AKI and those with impending and established AKI, use of interventions that are potentially nephrotoxic should be balanced against their expected benefit.

    Academic text (2016)
  • The frequency of ATN can be reduced dramatically by close attention to systemic hemodynamics and careful choice and dosing of potentially nephrotoxic drugs in high-risk subjects.

    Academic text (1995)
  • Patients should be monitored carefully when receiving nephrotoxic drugs to avoid kidney damage.

  • Certain antibiotics can be nephrotoxic, leading to serious complications for those with existing kidney issues.

  • The doctor explained that the nephrotoxic effects of some chemotherapy agents could harm the patients' kidneys.

Synonyms

toxic
vsnephrotoxic
395 4.0

Containing poison that can cause harm or death

is limited to harming the kidneys rather than causing general bodily harm

Surface Forms

nephrotoxic positive

Morphology

nephrotoxic = toxic (semi-transparent) = nephro + toxic

The combining form 'nephro-' means 'kidney' but is a specialist medical form; learners who know 'toxic' may not know 'nephro-', so partial transparency.

Etymology

Nephrotoxic joins nephro- 'kidney' and toxic 'poison', so it literally means a 'poison for the kidneys'. That's why it describes a substance that can damage the kidneys.