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muscarinic

muscarinic

1 9.5
Relating to parts of the nervous system that respond to the chemical muscarine
  • adjective
  • /ˌmʌskəˈrɪnɪk/
  • Specialized
translation icon : muscarínico
  • These investigators used methacholine as a muscarinic agonist and endothelium-dependent vasodilator.
  • muscarinic receptor
  • muscarinic receptor subtypes

Examples

  • Tiotropium is structurally similar to ipratropium, but with significantly higher affinity for muscarinic receptors within the lung.

    Academic text (2017)
  • Thus, a dysfunctional balance between muscarinic and adrenergic cardiac receptor activity may originate changes in both heart rate and cardiac muscle contractility.

    Academic text (2016)
  • Bovine brain studies have also revealed that muscarinic receptors are found in the vestibular nuclei.

    Academic text (2005)
  • However, a study on isolated rabbit hearts found that muscarinic receptor stimulation through carbachol improved functional recovery in isolated hearts.

    Academic text (2016)
  • Pilocarpine is a naturally occurring alkaloid with cholinergic properties that acts as an agonist at muscarinic receptors.

    Academic text (1999)
  • Saliva secretion is the result of cholinergic stimulation of muscarinic receptors within the salivary glands.

    Academic text (1999)
  • In situ hybridization studies of the rat brain have demonstrated a unique distribution of muscarinic receptor subtypes (n7, n8).

    Academic text (2005)
  • The capitalized designations M1, M2, and M3 represent pharmacologic definitions, which are based on the actions of various drugs that bind muscarinic receptors selectively.

    Academic text (2005)
  • Thus, the difference between methacholine and acetylcholine probably relates to differential actions of the two agents on muscarinic receptor subtypes, as has been suggested to explain the differences in the actions of carbachol and acetylcholine on endothelium-dependent relaxation.

    Academic text (1992)
  • Muscarinic receptors play a crucial role in regulating muscarinic signaling and are essential for many bodily functions.

How Parasympathetic

parasympathomimetic
  • Specialized
9.9
muscarinic
  • Specialized
1 9.5
cholinergic
  • Specialized
1 9.2
anticholinergic
  • Specialized
1 9.5

Surface Forms

muscarinic positive

Morphology

muscarinic = muscarine (opaque) = muscarine + ic

The term 'muscarinic' refers to the effects related to muscarine, which is not a common word known to most learners.

Etymology

Muscarinic comes from muscarine, a chemical first found in the red mushroom called the fly agaric, Amanita muscaria, and the mushroom's name comes from Latin musca meaning 'fly'. So muscarinic describes the receptors or effects in the body that respond to that chemical.