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mononitrate

mononitrate

6.8
A chemical that contains one nitrate group used in food or medicine
  • noun
  • /ˌmɒnoʊˈnaɪtreɪt/
  • Specialized
translation icon : mononitrato
  • Doctors often prescribe isosorbide mononitrate to help prevent chest pain in patients with certain heart conditions.
  • isosorbide mononitrate
  • mononitrate plus nadolol
  • mononitrate group

Examples

  • Five patients had to be withdrawn from isosorbide mononitrate treatment because of severe headaches.

    Academic text (1996)
  • Patients receiving both drugs received nadolol as above; then isosorbide mononitrate was added starting with 10 mg orally twice daily, which was increased to 20 mg unless hypotension or severe headache occurred.

    Academic text (1996)
  • The probability of death was only slightly lowered by the addition of isosorbide mononitrate in this study because there were few deaths related to bleeding.

    Academic text (1996)
  • The cumulative risk of bleeding was lowered by more than 50% in the nadolol plus isosorbide mononitrate group.

    Academic text (1996)
  • In patients receiving isosorbide mononitrate, intolerable headache was also judged to be a side effect necessitating cessation of that drug.

    Academic text (1996)
  • The combination of nadolol and isosorbide mononitrate is more effective than nadolol alone in preventing variceal bleeding in relatively well patients with cirrhosis.

    Academic text (1996)
  • Isosorbide mononitrate enhances the portal hypotensive effect of b-blockers, and decreases the number of patients classified as poor responders according to haemodynamic criteria.

    Academic text (1996)
  • We aimed to test the effectiveness of isosorbide mononitrate as an adjunct to the beta-blocker nadolol in the prophylaxis of first variceal bleeding in these patients.

    Academic text (1996)
  • When the four cases of portal hypertensive gastropathy were combined with variceal bleeding, the risk of bleeding in patients allocated nadolol plus isosorbide mononitrate was also significantly lower than that of patients randomized to nadolol alone.

    Academic text (1996)
  • The cumulative risk of variceal bleeding at the end of the study period was 18% in the nadolol group and 7.5% in the nadolol plus isosorbide mononitrate group (log-rank test: p=0.03; figure 2).

    Academic text (1996)

Synonyms

nitrate
vsmononitrate
  • Specialized
53 5.1

A chemical salt containing nitrogen and oxygen used in fertilizers and explosives

is a specific compound with one NO3 group used as food additive or medicine

Surface Forms

mononitrate singular
mononitrates plural

Morphology

mononitrate = nitrate (transparent) = mono + nitrate

The compound is transparently built from mono- plus nitrate, indicating a substance with one nitrate group.

Etymology

Mononitrate as a noun comes from mono- meaning 'one' and nitrate related to 'nitrogen', so it names a compound with exactly one nitrate group that is often used in foods, supplements, or medicine.