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Glite Dictionary
🧬 Cell surroundings 🌱 A small area 🏢 Business surroundings
microenvironment

microenvironment

1 6.8
The area around a cell that has other cells and chemicals affecting it
  • noun
  • /ˌmaɪkroʊɪnˈvaɪrənmənt/
  • Specialized
translation icon : microambiente
  • The liver has a unique immune microenvironment that is biased toward tolerance, which contributes to the difficulty in treating HCC.
  • tumor microenvironment

So, so H&E; slides are not a very good way to get the proportions of the microenvironment.

Examples

  • Exosomes have multiple roles in the tumor microenvironment, and exosome-mediated communication is thought to be crucial for cancer cell survival.

    Academic text (2017)

  • Our data imply that smoking delivers toxins and nicotine to the uterine microenvironment that can affect microvascular health.

    Blog text (31)

  • So this is my motivation for studying the tumor microenvironment and try to use my bioinformatic skills just to help in this problem.

  • Alcohol induces an oxidized microenvironment within the lung.

    Academic text (2016)

  • Besides, changes in the tumor microenvironment in turn affect radiation-induced tumor repression.

    Academic text (2018)

  • In an attempt to further enhance targeted delivery of anti-miRs, a peculiar property of the tumor microenvironment was exploited: low pH in this instance.

    Academic text (2016)

  • One important factor influencing the epigenetic state of immune cell populations is extracellular signals derived from the tissue microenvironment.

    Academic text (2017)

  • We found that bSCs and dSCs are distinct cell populations with different transcriptomes and repair features, indicating that the microenvironment is a key regulator of the dedifferentiation program.

    Academic text (2017)

  • Meanwhile, 3D scaffolds also provide a supportive platform and mimic the bone marrow microenvironment, which enables the expansion and maintenance of an HSC supply and RBC production.

    Academic text (2013)

  • The cancer research team studied the cells within their microenvironment to understand how they interact with neighboring tissues.

Synonyms

environment
vsmicroenvironment
∞ 2.7

The people, places, and conditions around a person, animal, or thing that affect them

is the immediate biological setting that directly influences cell behavior
surroundings
vsmicroenvironment
112 2.5

The area and things near a person or place

is the immediate biological setting that directly influences cell behavior

How Local

microenvironment
  • Specialized
1 6.8
environment
∞ 2.7

Surface Forms

microenvironment singular
microenvironments plural

Morphology

microenvironment = environment (semi-transparent) = micro + environment

The form clearly means 'small environment', but the cell biology sense is a specialized extension of that basic compositional meaning.

Etymology

Microenvironment comes from micro- 'small' and environment 'surroundings', so it means a 'small surrounding'. That's why scientists use it for the immediate area around a cell or group of cells that affects how they behave.