methotrexate
4
7.6
- noun
- /ˌmɛθəˈtrɛkseɪt/
- Specialized
:
metotrexato
- Patients using methotrexate for psoriasis often report significant improvements in their skin condition.
- methotrexate and mercaptopurine
- DMARDs, such as methotrexate
- methotrexate or cyclophosphamide
Examples
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If maintenance chemotherapy with 6-mercaptopurine and methotrexate helps to cure ALL, how does it work?
Academic text (1992) -
Four patients were treated with intrathecal methotrexate and cytarabine, while the other was treated with methotrexate alone.
Blog text (17) -
One might also anticipate that drug resistance would occur when methotrexate is given continuously.
Academic text (1992) -
Other steroid-sparing agents are available, such as methotrexate and cyclosporin.
Academic text (1992) -
The triaging nurse notes that Mrs. X is currently taking methotrexate to treat her rheumatoid arthritis.
Academic text (2012) -
The most commonly used chemotherapeutic agents include doxorubicin, cisplatin, and high-dose methotrexate.
Academic text (2006) -
Disease-modifying anti-rheumatic drugs (DMARDs), especially methotrexate and biologic agents (Table 1), have proved a major advance in the management of RA.
Academic text (2014) -
Methotrexate is an antimetabolite antineoplastic agent that inhibits folate metabolism, thus interfering with DNA synthesis.
Academic text (2012) -
The doctor prescribed methotrexate to help control her rheumatoid arthritis symptoms.
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After starting treatment with methotrexate, he noticed a decrease in the severity of his joint pain.
Synonyms
1
7.9
A drug used to treat some cancers and diseases of the immune system
A toxic drug that stops cell growth by blocking folic acid, used to treat some cancers and arthritis
A medicine used to treat cancer and some immune system diseases by stopping cells from growing
Compounds
- Specialized
A medicine used to treat cancer and some immune system diseases by stopping cells from growing
Surface Forms
Etymology
Methotrexate was invented by chemists from name parts: metho- suggests 'methyl', a small chemical group, and -trexate is the rest of the drug name. So, the long name is a memory cue that this is a chemical medicine that blocks folic acid and so stops fast cell growth.