immunoprecipitation
- noun
- /ɪˌmjunəprɪsɪpɪˈteɪʃən/
- Specialized
- In the lab, we performed immunoprecipitation to detect the presence of antibodies in the serum samples.
- Chromatin immunoprecipitation
- immunoprecipitation (ChIP)
Examples
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Antibodies to the melanocytes have been detected by immunoprecipitation in the sera of patients with vitiligo.
Academic text (2007) -
The immunoprecipitation, RT-PCR, and electron-microscopic findings point to the expression of TF by both the a and cells but not by d or pancreatic polypeptide cells.
Academic text (2002) -
An analysis of the input for HSP70B immunoprecipitation.
Blog text (15) -
This approach, termed QUICK for QUantitative Immunoprecipitation,
Blog text (15) -
After crosslinking, chromatin was isolated from about 4 x 10^7 cells, which allows 2 to 3 different immunoprecipitations per sample at a time, and then processed as follows.
Academic text (2017) -
In this study, we explored the above questions through the use of RNA sequencing (RNA-seq) and chromatin immunoprecipitation sequencing (ChIP-seq).
Academic text (2017) -
Quantitative chromatin immunoprecipitation (qChIP) analysis was performed using a Corbett Life Science Rotor Gene 6000 machine.
Academic text (2017) -
Expression of tissue factor (TF) in the islet preparations was investigated by immunohistochemistry, immunoprecipitation, electron microscopy, and RT-PCR.
Academic text (2002) -
The researcher used immunoprecipitation to isolate the specific protein from the cell lysate for further analysis.
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During the experiment, immunoprecipitation was essential for purifying the antigen from the protein mixture.
Synonyms
A lab test that uses antibodies to find or measure proteins in samples like blood
A lab test that uses antibodies to find or measure proteins in body samples
Surface Forms
Morphology
immunoprecipitation = precipitation (semi-transparent) = immuno + precipitation
The compound is compositionally clear (immuno- + precipitation), but the specific laboratory technique sense using antibodies is technical and not obvious to general learners.
Etymology
Immunoprecipitation starts with immuno- meaning 'related to the body's immune protection' and ends with precipitation meaning 'falling out of a liquid', like rain. So it describes a lab method where immune proteins (antibodies) make a specific protein 'fall' out of the solution so scientists can pull it out and study it.