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immunoprecipitation

immunoprecipitation

1 9.3
A lab method that uses special proteins called antibodies to pull a specific protein out of a liquid
  • noun
  • /ɪˌmjunəprɪsɪpɪˈteɪʃən/
  • Specialized
translation icon : inmunoprecipitación
  • In the lab, we performed immunoprecipitation to detect the presence of antibodies in the serum samples.
  • Chromatin immunoprecipitation
  • immunoprecipitation (ChIP)

Examples

  • Antibodies to the melanocytes have been detected by immunoprecipitation in the sera of patients with vitiligo.

    Academic text (2007)
  • The immunoprecipitation, RT-PCR, and electron-microscopic findings point to the expression of TF by both the a and cells but not by d or pancreatic polypeptide cells.

    Academic text (2002)
  • An analysis of the input for HSP70B immunoprecipitation.

    Blog text (15)
  • This approach, termed QUICK for QUantitative Immunoprecipitation,

    Blog text (15)
  • After crosslinking, chromatin was isolated from about 4 x 10^7 cells, which allows 2 to 3 different immunoprecipitations per sample at a time, and then processed as follows.

    Academic text (2017)
  • In this study, we explored the above questions through the use of RNA sequencing (RNA-seq) and chromatin immunoprecipitation sequencing (ChIP-seq).

    Academic text (2017)
  • Quantitative chromatin immunoprecipitation (qChIP) analysis was performed using a Corbett Life Science Rotor Gene 6000 machine.

    Academic text (2017)
  • Expression of tissue factor (TF) in the islet preparations was investigated by immunohistochemistry, immunoprecipitation, electron microscopy, and RT-PCR.

    Academic text (2002)
  • The researcher used immunoprecipitation to isolate the specific protein from the cell lysate for further analysis.

  • During the experiment, immunoprecipitation was essential for purifying the antigen from the protein mixture.

Synonyms

immunoassay
vsimmunoprecipitation
  • Specialized
1 7.2

A lab test that uses antibodies to find or measure proteins in samples like blood

separates the target protein from solution rather than only measuring it
immunochemical assay
vsimmunoprecipitation
  • Specialized
6.6

A lab test that uses antibodies to find or measure proteins in body samples

focuses on pulling the protein out of solution rather than measuring it

Surface Forms

Morphology

immunoprecipitation = precipitation (semi-transparent) = immuno + precipitation

The compound is compositionally clear (immuno- + precipitation), but the specific laboratory technique sense using antibodies is technical and not obvious to general learners.

Etymology

Immunoprecipitation starts with immuno- meaning 'related to the body's immune protection' and ends with precipitation meaning 'falling out of a liquid', like rain. So it describes a lab method where immune proteins (antibodies) make a specific protein 'fall' out of the solution so scientists can pull it out and study it.