heteromeric
1
9.9
- adjective
- /ˌhɛtəˈrɒmɪrɪk/
- Specialized
:
heteromérico
- Researchers are investigating how heteromeric interactions improve the effectiveness of certain drugs.
Examples
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The first is direct heteromeric cooperative interactions between pairs of factors bound to adjacent sites in the genome that selectively increase occupancy only in regions where appropriately spaced sites for both factors occur 26-30.
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The study revealed that the heteromeric structure of the protein complex was essential for its function.
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In contrast, local genome accessibility is not altered, per se, by direct heteromeric cooperative interactions.
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No potential heteromeric interactions could be found in the model that would improve the prediction of DNA binding by these proteins, which are known to function in concert on a common pool of CRMs.
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A much larger role for direct heteromeric interactions in targeting transcription factor binding has been invoked, where it is assumed that the concentrations at which factors are expressed in cells are too low to allow significant occupation of functional target sites without such interactions 26-30.
Blog text (3) -
Our analysis does not rule out an important role for direct heteromeric cooperative interactions between transcription factors quantitatively modifying the binding of these proteins at a subset of recognition sequences.
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In such cases, since changed accessibility must affect DNA binding and do so in proportion to the degree of that change, any additional influences on DNA binding due to heteromeric cooperative interactions and other effects must be limited, at most, to the residual extent that altered DNA binding and accessibility do not correlate.
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The heteromeric combination of different enzymes allows for a more efficient catalytic process.
Synonyms
9
7.9
Made of different types of people or things, like scientists and artists
A thing that has different kinds of parts
Not the same type of cell or structure
Made of different parts that are not the same throughout
How Heterogeneous
Surface Forms
Morphology
heteromeric = heteromer (semi-transparent) = hetero + mer + ic
The relation 'heteromer' → 'heteromeric' is a standard adjectival formation but the base term is technical and relies on a combining form ('mer') unfamiliar to many learners.
Etymology
The word heteromeric comes from hetero- meaning 'different' and -meric meaning 'part', the same idea you see in polymer ('many parts'). So a heteromeric molecule or complex is made of 'different parts', which is why we use it for structures with different subunits.