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exosome

exosome

1 8.7
A tiny bubble that cells release to carry proteins or genes to other cells
  • noun
  • /ˈɛk.səˌsoʊm/
  • Specialized
: exosoma
  • The creation of an immunosuppressive microenvironment is an important component of tumor pathogenesis, and exosomes have been implicated in many immunosuppressive processes 33-35.
  • exosome-derived
  • exosome-mediated
  • exosome-mediated communication

So in work by a group down under have been looking at placental exosomes over pregnancy.

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Examples

  • The research detailed here indicates that exosomes may have potential as biomarkers for the diagnosis of liver pathology.

    Academic text (2017)
  • The suppressive effect was more pronounced after the second administration of AMSC-exosomes and in smaller tumors.

    Academic text (2017)
  • Exosome-directed research in the area of primary liver disease has progressed over the last decade.

    Academic text (2017)
  • Angiogenesis may also be stimulated by exosomes released under hypoxic conditions.

    Academic text (2017)
  • Exosomes have multiple roles in the tumor microenvironment, and exosome-mediated communication is thought to be crucial for cancer cell survival.

    Academic text (2017)
  • The cellular membrane that envelops exosomes helps to protect the cargo from enzymatic degradation.

    Academic text (2017)
  • Table 2 summarizes the role of exosomes in the differential diagnosis between HCC and other liver pathologies.

    Academic text (2017)
  • The cancer-associated protein TGM2 is secreted through an exosome-mediated non-classical secretion pathway and may be a valuable tumor marker.

    Academic text (2017)
  • AMSC-derived exosomes facilitated HCC suppression mainly by increasing intratumoral and circulating NK cells 77, 80.

    Academic text (2017)
  • The exosome is a tiny bubble-like vesicle that aids in communication between cells.

Synonyms

vesicle
vsexosome
  • Specialized
3 7.9

A small sac in living things that holds fluid

is a tiny sac released by cells to transfer proteins and genetic material
liposome
vsexosome
  • Specialized
1 9.3

A tiny bubble made of fat that carries medicine into cells

is a natural tiny sac made by cells to transfer proteins and genetic material

Surface Forms

exosome singular
exosomes plural

Morphology

exosome = exo + some

Although analyzable as 'exo-' + '-some', the components are Greek combining forms unfamiliar to general learners and the biological sense is specialized, so the meaning is not recoverable from common English words.

Etymology

Exosome comes from the parts exo- meaning 'outside' and -some meaning 'body', as in ribosome. So an exosome is literally a small 'body' that goes out from a cell to carry proteins or genetic material to other cells.