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exosome

exosome

1 9.9
A group of proteins inside cells that breaks down and processes RNA
  • noun
  • /ˈɛk.səˌsoʊm/
  • Specialized
: exosoma
  • exosome test

Examples

  • Several in vitro and in vivo studies have proposed the concept of exosome-mediated cancer therapies.

    Academic text (2017)
  • However, these limitations in the understanding of the functional or pathophysiological role of exosome lncRNA do not impact their potential utility as disease biomarkers 64,65.

    Academic text (2017)
  • The ability to selectively manipulate exosome content, through either exogenous or endogenous approaches, may offer further opportunities for unique therapies.

    Academic text (2017)
  • Vps4A and other key regulators of exosome biogenesis have been demonstrated to be down-regulated in HCC tissues.

    Academic text (2017)
  • Additionally, growth factors are released in the tumor microenvironment to support the growth of CSCs, thereby creating a positive feedback loop that may be the result of exosome production and may result in poor prognosis for some 71,73.

    Academic text (2017)
  • Researchers are studying the role of exosomes in transferring RNA between different cells.

  • Scientists have discovered that exosomes can influence the behavior of surrounding cells by carrying specific RNA molecules.

  • The team's analysis focused on how exosomes help in the degradation and processing of RNA within eukaryotic cells.

Surface Forms

exosome singular
exosomes plural

Morphology

exosome = exo + some

The term is formed from Greek combining forms 'exo-' (outside) + '-some' (body/particle) which are technical and not productive or familiar to B1 learners, so the meaning cannot be derived from everyday English base words.

Etymology

Exosome comes from the parts exo- meaning 'outside' and -some meaning 'body', like in ribosome. A helpful way to remember the cellular exosome complex is to think of it as a small 'body' that takes RNA pieces away or removes faulty RNA, which fits its job of processing and breaking down RNA.