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dysregulation

dysregulation

1 8.8
Abnormal control of body processes like hormones or the immune system that often causes illness
  • noun
  • /ˌdɪsˈrɛɡjʊˌleɪʃən/
  • Specialized
: disregulación
  • Generally, exposure to trauma may contribute to global psychophysiological dysregulation, increasing the risk for the development of psychopathology.10
  • immune dysregulation
  • epigenetic dysregulation

Among other things, I think maybe dysregulation of lipids as well.

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Examples

  • Therefore, if frailty describes a multisystem phenotype due to multiple physiologic dysregulation, sarcopenia is likely to be the muscular manifestation of that phenotype.

    Academic text (2017)
  • Food intolerances are often related to gastrointestinal immune dysregulation, which can result in chronic inflammation.

    Academic text (2018)
  • And, and I think that there are parents who will report wow, like there are, there is immune system dysregulation in my child.

  • Loss of AMH function caused the dysregulation of sexual development.

    Academic text (2017)
  • To treat it, you need to treat the Hashimoto's itself, which means addressing the immune dysregulation.

    Blog text (31)
  • From moods to pain, our brain chemicals affect every aspect of our lives, and we've seen how dysregulation can lead to all sorts of problems.

  • However, germ-free mice do not just have an immature immune system; they also display signs of immune dysregulation.

    Academic text (2016)
  • Karma (1997) has proposed that a dysregulation of central monoamine function underlies out-of-control sexual behavior.

    Academic text (2004)
  • We investigated whether depressive symptoms and antidepressant use are associated with biomarkers for glucose dysregulation and inflammation, body mass index (BMI), and waist circumference. Methods.

    Academic text (2013)
  • Esther's arthritis is a disease that involves dysregulation of the immune system, leading to increased inflammation and discomfort.

Synonyms

disorder
vsdysregulation
  • Specialized
515 4.3

A health condition in which the body or mind do not work normally

focuses on abnormal control that can cause that disturbance
uncontrollability
vsdysregulation
1 8.6

A situation when something cannot be stopped or managed

indicates impaired or abnormal control rather than complete loss

Surface Forms

dysregulation singular

Morphology

dysregulation = regulation (semi-transparent) = dys + regulate + ion

Meaning is compositionally clear but the Greek prefix 'dys-' is somewhat specialized.

Etymology

Dysregulation starts with dys- meaning 'bad' or 'difficult' and the part regulation, meaning 'control' (as in regulate or regular). In health, dysregulation means the body's normal control of processes like hormones or the immune system is not working, which can lead to illness.