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⚗️ Removal in chemistry 🛡️ Loss of protection
deprotection

deprotection

8.9
Removing a chemical group from a molecule that was added to stop other reactions when making a compound
  • noun
  • /ˌdiːprəˈtɛkʃən/
  • Specialized
translation icon : desprotección
  • In chemical synthesis, deprotection is the essential step that removes the protective group to reveal the active site.
  • acid-catalyzed deprotection
  • deprotection reaction
  • catalyzed deprotection

Examples

  • Because deprotection can occur at room temperature in this system, a PEB is not essential for imaging.

    Academic text (2001)

  • At the highly exposed region of the film, close to the air-film interface, the acid concentration is high, causing deprotection to proceed rapidly, quickly reaching 100% deprotection.

    Academic text (2001)

  • The rate of the deprotection reaction is an increasing function of the concentration of acid.

    Academic text (2001)

  • The data in Figure 8 indicate that the contribution of the deprotection chemical processes to image spreading is a constant fraction of the image size.

    Academic text (2001)

  • Part (a) shows the predicted evolution of deprotection for the standard case in which no base was added to the resist film.

    Academic text (2001)

  • The deprotection kinetics are correctly predicted using the PN model.

    Academic text (2001)

  • The mobility of PFBS-A decreases sharply as the polymer undergoes deprotection.

    Academic text (2001)

  • Consideration of the limiting case in which diffusion is negligible highlights the role deprotection kinetics play in image spreading.

    Academic text (2001)

  • Within each subfilm, the full set of thermal and acid-catalyzed deprotection reactions can take place, and transport of the acid can occur between adjacent subfilms.

    Academic text (2001)

  • In contact with an aqueous alkaline developer, the carboxylic acid groups formed during deprotection will ionize, rendering the polymer soluble in the aqueous solution.

    Academic text (2001)

Synonyms

deacetylation
vsdeprotection
  • Specialized
9.6

Removing a small chemical group called acetyl from a molecule

is the general removal of protective groups rather than a specific one
demethylation
vsdeprotection
  • Specialized
8.6

The process of removing a small chemical part called a methyl group from a molecule

is broader in scope removing protective groups not just methyl groups
deaminization
vsdeprotection
  • Specialized
9.9

Removing a small nitrogen part from a protein building block or similar chemical

focuses on removing protective groups generally not a single amino group
deamination
vsdeprotection
  • Specialized
7.9

A process that removes an amino group from an amino acid in the body

is the general removal of protective groups not limited to metabolism
deamidation
vsdeprotection
  • Specialized
9.9

A chemical change that removes or alters an amide group in a molecule, often a protein

covers removal of protective groups rather than altering amide bonds
decarboxylation
vsdeprotection
  • Specialized
8.7

Removal of a small part from a molecule that releases carbon dioxide and changes it

is about removing protective groups generally rather than releasing carbon dioxide

Antonyms

protection
974 1.0

Keeping people or things safe from harm

Surface Forms

deprotection singular
deprotections plural

Morphology

deprotection = deprotect (semi-transparent) = de + protect + ion

Adding '-ion' to the verb 'deprotect' straightforwardly forms a noun meaning the act or process of deprotecting.

Etymology

Deprotection starts with de- meaning 'remove' and the word protect meaning 'to keep safe'. In chemistry it is like taking off a coat that was protecting a part of a molecule so that part can react. So deprotection is the process of removing a protective group.