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autoinhibited

autoinhibited

9.3
Unable to act because a part of itself stops it
  • adjective
  • /ˌɔːtoʊɪnˈhɪbɪtɪd/
  • Specialized
: autoinhibido
  • Researchers discovered that the enzyme is autoinhibited by a segment of its own structure.

Examples

  • In this state, the protein remains autoinhibited until a signal is received.

  • In its autoinhibited form, the molecule cannot perform its normal biological function.

  • The protein remains autoinhibited until it interacts with a specific signaling molecule.

  • The enzyme is autoinhibited by its own structure.

  • The protein remains autoinhibited until it interacts with a specific signaling molecule.

  • Researchers discovered that the enzyme is autoinhibited by a segment of its own structure.

  • In its autoinhibited form, the molecule cannot perform its normal biological function.

How Inhibited

autoinhibited
  • Specialized
9.3
inhibited
12 6.0
regulated
44 4.1
active
232 1.0

Surface Forms

autoinhibited positive

Morphology

autoinhibited = inhibited (semi-transparent) = auto + inhibit + ed

The structure is clear, but the molecule/process sense relies on a technical scientific extension of self-inhibition.

Etymology

Autoinhibited is made of auto- ('self') and inhibit ('to hold back'), like the auto- in automatic. So, it describes a protein or molecule that 'holds itself back' and cannot work until something else changes it.