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Glite Dictionary
🧬 Opposite DNA strand 🧬 Gene-blocking molecule
antisense

antisense

1 9.2
A strand of DNA or RNA that matches and attaches to messenger RNA
  • adjective
  • /ˈæntiˌsɛns/
  • Specialized
: antisentido
  • Alternatively, some types of short antisense sequences can be synthesized in vitro and added directly to cell culture medium.
  • antisense RNA
  • antisense drugs
  • gene with antisense

Examples

  • The antisense strand of DNA is designed to match with the target coding sequence, effectively blocking protein production.

  • Equally astonishing is the extent of antisense transcription, both within and around annotated genes and within nonannotated regions.

    Academic text (2010)

  • Extinguishing gene function with antisense RNA and DNA.

    Academic text (1992)

  • This is the antisense approach and makes use of the so-called antisense oligonucleotides 17, 18.

    Academic text (2016)

  • Basically, two major approaches exist for delivery: viral and non-viral, and depending on whether antisense inhibition or replacement is desired, the appropriate approach(es) are utilized.

    Academic text (2016)

  • For the first round of PCR, we used antisense primer 1, sense primer TATGGGCATGGHATHCCYCT, and Taq-DNA polymerase (GIBCO BRL).

    Academic text (1996)

  • For example, in studies of tobacco plants, an antisense version of the gene coding for the small subunit of Rubisco was inserted, resulting in a range of genotypes with variable amounts of the Rubisco protein, which is responsible for carbon fixation in photosynthesis.

    Academic text (2000)

  • In gene therapy, researchers often use antisense RNA to inhibit the expression of specific genes.

  • Using antisense oligonucleotides allows scientists to study gene function by preventing its expression in cells.

Surface Forms

antisense positive

Morphology

antisense = sense (semi-transparent) = anti + sense

The word is built transparently from anti- + sense, but its biological use is a specialized technical meaning that is not fully predictable for a beginner.

Etymology

Antisense comes from the parts anti- 'against' and sense 'the coding message'. It describes an adjective form of a strand that is opposite the sense strand, so it matches the code and can bind to it to block the gene's message.