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transcriptase

transcriptase

1 9.3
A protein in cells that makes RNA from DNA
  • noun
  • /trænsˈkrɪpteɪs/
  • Specialized
translation icon : transcriptasa
  • The scientists use an enzyme called reverse transcriptase to match up the RNA to a version of the DNA from which it originated.
  • reverse transcriptase
  • transcriptase inhibitors
  • nucleoside reverse transcriptase

Examples

  • Second, the virus polymerase also functions as a reverse transcriptase.

    Academic text (1994)
  • RNA viruses use reverse transcriptase to copy themselves into DNA in host cells, and retrotransposons also use the enzyme.

    Academic text (1998)
  • Yeah, it's the transcriptase and it's attached to something.

  • It goes after reverse transcriptase only.

  • But you've also heard throughout the course how handy this reverse transcriptase material is.

  • Wasting no time, the virus deploys the reverse transcriptase it has brought along.

    Academic text (2005)
  • A cDNA library is prepared from isolated cellular mRNAs using the enzyme reverse transcriptase.

    Academic text (1992)
  • Researchers also probed the origins of the telomerase system by searching for clues in reverse transcriptase, an enzyme that is not unique to telomerase.

    Academic text (1998)
  • First-strand cDNA synthesis was performed using Superscript Reverse Transcriptase (Invitrogen, Carlsbad, CA) according to the manufacturer's protocol.

    Academic text (2014)
  • The researchers utilized transcriptase to synthesize RNA, allowing for precise genetic studies.

Synonyms

polymerase
vstranscriptase
  • Specialized
5 9.6

A protein that builds DNA or RNA by joining small parts to an existing strand

is limited to producing RNA from a DNA template, not both DNA and RNA
RNA polymerase
vstranscriptase
  • Specialized
1 6.3

A protein in cells that makes RNA by copying DNA

has the same function but is a more specific technical name

Compounds

reverse transcriptase
  • Specialized
1 6.3

An enzyme that makes DNA from RNA, often used by viruses like HIV

A drug that stops HIV changing its genetic material and is used with other medicines

An HIV drug that joins viral DNA and stops the enzyme that copies the virus

A drug that stops an enzyme viruses like HIV use to copy their genes

Surface Forms

transcriptase singular

Morphology

transcriptase = transcript (semi-transparent) = transcript + ase

Formed from 'transcript' + the enzyme-forming suffix '-ase'; the relation is clear in scientific contexts but '-ase' is specialist vocabulary that B1 learners may not know.

Etymology

Transcriptase comes from trans- ('across') and script ('write'), with -ase marking an 'enzyme'. So a transcriptase is like a small 'writer' that copies information across from DNA into RNA, which explains its modern meaning.