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spironolactone

spironolactone

1 8.2
A medicine that reduces extra water in the body and lowers high blood pressure
  • noun
  • /ˌspaɪrənoʊˈlæktəˌoʊn/
  • Specialized
translation icon : espironolactona
  • A combination of potassium-losing loop diuretics like furosemide with a potassium-sparing diuretic like spironolactone is the best approach.
  • patients prescribed spironolactone
  • spironolactone 50 mg

Examples

  • At this stage, however, an aldosterone antagonist is often introduced, such as spironolactone or eplerenone.

    Academic text (2011)
  • Spironolactone, used in combination with a loop diuretic, is a useful adjunct.

    Academic text (2011)
  • Care should be taken with the use of spironolactone in these patients because of the risk of hyperkalaemia.

    Academic text (2003)
  • In older patients treated with spironolactone, is the use of TMP-SMX or other antibiotics associated with the risk for sudden death?

    Academic text (2015)
  • In patients receiving spironolactone, the death rate within 14 days of antibiotic use is relative to the total number of prescriptions.

    Academic text (2015)
  • There are two aldosterone blockers licensed for use: spironolactone and eplerenone.

    Academic text (2011)
  • In the RALES trial, mortality was reduced by about 30% when spironolactone was added to an ACE inhibitor, diuretic, and digoxin.

    Academic text (2011)
  • In patients with symptomatic heart failure with relatively preserved ejection fraction (HFpEF), does spironolactone improve clinical outcomes?

    Academic text (2014)
  • If the patient continues to have symptoms, then spironolactone (an aldosterone antagonist) may be added, particularly in patients post-MI or with NYHA classification 3-4.

    Academic text (2011)
  • The doctor prescribed spironolactone to help manage her high blood pressure.

Synonyms

Aldactone
vsspironolactone
  • Specialized
1 7.5

A medicine that treats high blood pressure and some hormone problems

is the generic steroid medicine used to treat the same conditions

Surface Forms

Etymology

Spironolactone mixes two parts: spiro- meaning 'spiral' and -lactone from lact- meaning 'milk', the same root as in lactose. The name describes parts of the drug's chemical shape, so it helps you remember this particular medicine used for high blood pressure and fluid build-up.