restriction site
- noun
- /rɪˈstrɪkʃən saɪt/
- Specialized
- And here the unique thing was that there's a restriction site inside that is is present in normal DNA and not present in in sickle DNA.
Examples
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The genetic engineer identified a restriction site on the DNA strand for the experiment.
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We'll use, we'll say, restriction site K and A here.
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A small proportion of uncut DNA could be explained by errors introduced into the restriction sites by the Tag polymerase.
Academic text (1992) -
Thus, complexity reduction is achieved by excluding genomic regions where the distance between specified restriction sites is greater than the threshold determined by PCR.
Academic text (2010) -
To insert the new gene, the scientists carefully analyzed the restriction sites to ensure proper cuts in the DNA.
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Understanding the location of each restriction site is crucial before performing the cloning procedure.
Surface Forms
Morphology
The compound is partially compositional: 'site' = location and 'restriction' suggests limitation, so a learner could infer it refers to a particular place where some restricting happens. However the specific technical sense (‘a DNA sequence where a restriction enzyme cuts’) is domain-specific and not derivable from everyday meanings without biological knowledge, so it is only partially transparent to a B1 learner.
Etymology
Restriction site comes from lab work with DNA. It means a small site or place on the DNA where a protein called a restriction enzyme stops and cuts the molecule. Think of it as a tiny 'cut here' sign on the DNA, so the phrase means the exact place on DNA where an enzyme can 'cut'.