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Glite Dictionary
pyrazinamide

pyrazinamide

1 9.8
A medicine used with other medicines to treat tuberculosis
  • noun
  • /ˌpaɪrəˈzɪnəˌmaɪd/
  • Specialized
: pirazinamida
  • Pyrazinamide is a commonly used first-line antitubercular drug. Gastric-related adverse drug reactions are common with pyrazinamide.
  • pyrazinamide, ethambutol
  • pyrazinamide, isoniazid
  • pyrazinamide monoresistance

Examples

  • Daily ATT was initiated in this patient with isoniazid, rifampin, ethambutol, and pyrazinamide.

    Academic text (2007)

  • The role of ethambutol and pyrazinamide for the treatment of MDR TB is unclear.

    Academic text (2015)

  • A few days later, urticaria was observed following a single dose of pyrazinamide.

    Academic text (2007)

  • We could not locate any similar reports of maculopapular rash due to pyrazinamide.

    Academic text (2007)

  • The patient was rechallenged with pyrazinamide, which led to the occurrence of a similar type of rash.

    Academic text (2007)

  • Rarely, skin rashes and photosensitivity are reported during the treatment of pyrazinamide.

    Academic text (2007)

  • Susceptibility to fluoroquinolone and pyrazinamide was not routinely tested.

    Academic text (2013)

  • We report a case of erythematous maculopapular rash caused by pyrazinamide in a patient treated for tuberculosis.

    Academic text (2007)

  • In our cohort, 97.6% and 45.0% of MDR TB strains were tested for resistance to ethambutol and pyrazinamide, respectively.

    Academic text (2015)

  • The doctor prescribed pyrazinamide along with rifampicin to ensure the patient's successful recovery from tuberculosis.

Surface Forms

pyrazinamide singular
pyrazinamides plural

Morphology

pyrazinamide = pyrazine (opaque) = pyrazine + amide

Although the word is formally based on 'pyrazine' plus the chemical suffix '-amide', the resulting drug name is not meaningfully guessable for an average learner from those parts alone.

Etymology

Pyrazinamide comes from two chemical parts: pyrazine, a kind of chemical 'ring' found in some medicines, and amide, a common chemical 'ending' that marks a type of molecule. So the name shows it is the 'amide' form of a pyrazine compound, which helps explain why this word is the name of a specific drug used to treat tuberculosis.