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polypeptide

polypeptide

2 6.6
A long chain of at least ten amino acids joined together
  • noun
  • /ˌpɑːliˈpɛptaɪd/
  • Specialized
translation icon : polipéptido
  • The polypeptide had a molecular mass of 47 kDa, identical to that of TF 4.
  • pancreatic polypeptide
  • molecular-weight polypeptides

And that these polypeptide substrates have complex native folds.

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Examples

  • According to his computer program, his E. coli polypeptide should have worked, but it didn't.

    Fiction book (2000)
  • Protein structures turned out to be too complicated for model building from the known structures of polypeptide components.

    Academic text (1995)
  • Well, it's a polypeptide, this unit right in here.

  • As it stands, no polypeptide is made beyond that.

    Fiction book (2000)
  • That mRNA gets translated by a ribosome into a polypeptide chain or a protein.

  • Actually, it's quite a feat for either male or female to predict how a stretch of polypeptide will contort, curl, and fold.

    Fiction book (2000)
  • The basis for this "theorem" is the degeneracy of the genetic code: a given polypeptide sequence can be encoded by different DNA sequences.

    Academic text (1996)
  • In this six-part series, we will evaluate one claim: that many random polypeptide sequences fold into a single stable conformation.

    Blog text (13)
  • She's very good with shapes, how the pump orifice is configured, how the polypeptide must fold in order to match, and so on.

    Fiction book (2000)
  • The synthesis of polypeptide chains is crucial for the development of new medications.

Synonyms

peptide
vspolypeptide
  • Specialized
11 5.8

A short chain of amino acids that forms part of proteins

is a longer chain of ten or more amino acids

How Long

protein
  • Specialized
435 2.8
polypeptide
  • Specialized
2 6.6
dipeptide
  • Specialized
1 6.9

Surface Forms

polypeptide singular
polypeptides plural

Morphology

polypeptide = peptide (semi-transparent) = poly + peptide

The word is compositionally built from poly- 'many' plus peptide, but the specialized biochemical sense may not be immediately obvious to non-specialists.

Etymology

Polypeptide breaks into poly- meaning 'many' (the same poly- in polygon) and peptide, from a Greek word meaning 'to digest' that came to mean small pieces of protein; so a polypeptide is literally a chain of 'many' protein pieces, which explains why it is a long molecule made of many amino acids.