plasmid DNA
1
4.6
- noun
- /ˈplæzmɪd diˈɛnˈeɪ/
- Specialized
:
ADN plasmídico
- Scientists use plasmid DNA to transfer genes into bacterial cells for research.
Examples
-
Perform gel electrophoresis to make sure the majority of plasmid DNA is in supercoiled or closed circular form.
Blog text (1) -
By inserting a gene into plasmid DNA, researchers can create a vector for gene therapy.
-
Delivery of plasmid DNA by tattooing.
Blog text (1) -
Increase the concentration of plasmid DNA solution by 2- to 5-fold.
Blog text (1) -
Then move the oscillating needle gently and slowly in a linear fashion to deliver plasmid DNA over the entire tattooing area.
Blog text (1) -
It takes microgram quantities of intact plasmid DNA, and even then expression levels are low without special help, such as the "gene gun" or other techniques.
Blog text (32) -
Indeed, some of the earliest experiments studying gene regulation in rat muscle by direct injection of plasmid DNA were performed in the laboratory where I did my PhD work, and even now I know investigators who are working on DNA vaccines.
Blog text (32) -
Nucleic acid-based vaccination is a topic of growing interest, especially plasmid DNA (pDNA) encoding immunologically important antigens.
Blog text (1) -
The laboratory extracted plasmid DNA to study its replication process independently from chromosomal DNA.
Synonyms
5
8.4
A small circular piece of DNA in a cell that can copy itself
Surface Forms
Morphology
The phrase 'plasmid DNA' is transparently compositional: 'plasmid' denotes a small, separate DNA molecule and 'DNA' names the hereditary molecule, so together they refer to DNA that is a plasmid. Although the concept is technical, the constituent meanings directly predict the compound and similar noun–noun constructions exist cross-linguistically, so a learner who knows both words would understand the MWE.
Etymology
Plasmid DNA comes from the word plasmid, based on 'plasma' meaning 'something formed', and DNA for the cell's genetic material, so it gives the image of a small, formed piece of DNA. That's why plasmid DNA means a small circular DNA molecule that sits apart from the cell's main DNA and can copy itself.