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perineurium

perineurium

9.9
A thin layer of tissue that surrounds and protects a bundle of nerve fibers
  • noun
  • /ˌpɛrɪˈnɜrɪəm/
  • Specialized
: perineurio
  • The perineurium acts as a protective layer, ensuring the nerve fibers within a bundle remain insulated from damage.
  • perineurium and epineurium

Examples

  • On further examination, the overgrown epineurium, perineurium, and endoneurium are disorganized; however, the surrounding tissue demonstrates no involvement or inflammation.

    Academic text (2015)
  • Frozen-section analysis reveals that the carcinoma has infiltrated the perineurium around a nerve fiber (arrow) (H&E; original magnification × 100).

    Academic text (2004)
  • During the healing process, collagen synthesis due to fibroblastic activity increases in the endoneurium and the perineurium.

    Academic text (2015)
  • It is reasonable to suspect that malignant cells with this ability express cell-surface molecules that enable them to initially traverse the perineurium.

    Academic text (2004)
  • The tumor originates from fatty infiltration of the nerve bundle infiltrating the epineurium and perineurium (12, 14).

    Academic text (2015)
  • In her research, she focused on how the perineurium contributes to the overall structure and function of the nerve fascicle.

  • The doctor explained that the perineurium is crucial for maintaining the integrity of nerve conduction.

Surface Forms

perineurium singular
perineuria plural

Morphology

perineurium = neurium (opaque) = peri + neur + ium

The term is derived from Greek roots and is specialized medical terminology, not easily deduced by learners without specific knowledge.

Etymology

The word perineurium breaks into parts: peri- meaning 'around', as in perimeter, and neur- meaning 'nerve', as in neuron, with -ium for a tissue or membrane. So, perineurium is the tissue that wraps 'around' a bundle of nerve fibers.