perineurial

9.9

Relating to the area around a nerve, especially the thin layer that covers nerve fibers

adjective

Specialized

: perineural

The perineurial sheath protects the nerve fibers from injury and helps regulate their environment.

Examples

For claudin-1, the intensity of staining was also graded as weak, moderate, or strong, with immunoreactivity of perineurial cells in normal peripheral nerve tissue as a reference for strong staining.

Academic text (2007)
As expected, claudin-1 was expressed in the (perineurial) capsule of schwannoma and was negative in smooth muscle, normal brain tissue, and fibroblasts.

Academic text (2007)
Researchers found changes in the perineurial structures in patients with nerve damage.
During the surgery, the doctor carefully examined the perineurial layer to ensure the nerves were undamaged.

Synonyms

perineural

vsperineurial

Specialized

1 8.4

Tissue that lies around a nerve

refers specifically to the sheath around nerve fibers

Surface Forms

perineurial positive

Morphology

perineurial = perineurium (semi-transparent) = peri + neur + ial

The adjective is regularly formed from the technical noun 'perineurium', but the medical specialization makes it less immediately accessible to many learners.

Etymology

Perineurial breaks into peri- meaning 'around' and neur- meaning 'nerve', as in neuron. So it means the layer 'around the nerve', the covering that protects nerve fibers.