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paracrine

paracrine

1 8.5
A chemical a cell releases to change nearby cells
  • noun
  • /ˈpærəˌkraɪn/
  • Specialized
: sustancia paracrina
  • This paracrine function may be a strategy adopted by liver cancer cells to modulate their microenvironment, resulting in improved proliferation.
  • paracrine cytokines
  • paracrine level
  • autocrine and paracrine

Examples

  • In summary, our data demonstrated that different pro-inflammatory cytokines and treatment time had different effects on the biological characteristics of UCMSCs, such as proliferation, differentiation, and paracrine levels.

    Academic text (2018)
  • In addition to differentiating into specific types of cells for the replacement of pathological cells, MSCs also produce paracrine factors to suppress inflammation.

    Academic text (2018)
  • IFNs act in both autocrine and paracrine manners.

    Academic text (2007)
  • After cultivation for 72 hours, the culture supernatants were collected for the detection of the paracrine level.

    Academic text (2018)
  • Its paracrine-like secretions were specific and rare, essential to Dalka's enzyme operations.

    Fiction book (1994)
  • These results indicated that different pro-inflammatory cytokines have different effects on the paracrine cytokines of UCMSCs, and long-term exposure may not improve the immunomodulatory capacity of UCMSCs.

    Academic text (2018)
  • This may possibly be due to the secretion of some unknown paracrine factors by the placenta (maternal decidua), as the maternal part of WJ is in close vicinity to it.

    Academic text (2018)
  • Thus, smoldering autocrine/paracrine IFN-I may synergize with other signal pathways in the tumor or draining lymph nodes to drive the IDO+ regulatory pDCs.

    Academic text (2017)
  • The growth of nearby cells is influenced by the paracrine factors released by certain types of hormones.

  • Researchers studied how paracrine signals from immune cells affect the behavior of neighboring cells in the tissue.

Surface Forms

paracrine singular
paracrines plural

Etymology

Paracrine comes from Greek parts para- meaning 'beside' and -crine meaning 'to secrete', as in secrete and endocrine. A paracrine (noun) is a substance a cell sends out to affect nearby cells, not something carried far in the blood.