nucleophile

1 9.3

An atom or molecule that gives electrons to form a chemical bond

noun
/ˈnjuːklɪəˌfaɪl/

Specialized

: nucleófilo

Derivatization of starting materials to incorporate suitable leaving groups has also been explored, as has the use of various bases to deprotonate the alcohol nucleophile.
nucleophile attacks

Nevertheless, the reaction between the aldehyde and the nucleophile that phyolate is readily reversible.

Examples

Because the first step doesn't involve the nucleophile, only the second step.
A fluoride is a horrid nucleophile as we saw, right?
So that or some nucleophile here.
So the enol is going to be a very good nucleophile and it's going to attack the carbonyl.
A large variety of alcohol nucleophiles (including primary, secondary, tertiary, and functionalized examples) and allyl alcohol electrophiles have been screened.

Blog text (1)
In a nucleophilic reaction, the nucleophile donates an electron pair to form a new bond with the substrate.
The strength of a nucleophile depends on its ability to donate electrons to positively charged atoms.
During the chemical reaction, the nucleophile surrounded the carbon atom, forming a stable bond.

Surface Forms

nucleophile singular

nucleophiles plural

Morphology

nucleophile = nucleo + phile

Although the term is built from classical combining forms meaning roughly 'nucleus' and 'loving,' the technical chemical meaning 'electron-pair donor' is not transparently predictable for an average learner.

Etymology

The word nucleophile comes from nucleus meaning 'center' or 'kernel' and -phile meaning 'lover'. So a nucleophile is like a 'lover of the center' — in chemistry it looks for positive centers (nuclei) and gives an electron pair to make a bond.