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mitoxantrone

mitoxantrone

1 9.9
A drug used to treat some cancers and multiple sclerosis
  • noun
  • /ˌmaɪtəˈzæntrən/
  • Specialized
: mitoxantrona
  • The doctor prescribed mitoxantrone to help treat her aggressive cancer.
  • mitoxantrone 12 mg
  • mitoxantrone therapy
  • trial of mitoxantrone

Examples

  • The benefits of mitoxantrone therapy were observed without evidence of short-term toxic effects, and treatment was generally well tolerated.

    Academic text (2002)
  • We do not start mitoxantrone therapy in patients with left ventricular ejection fraction less than 50%.

    Academic text (2002)
  • Several pilot trials of mitoxantrone were effective and showed no adverse events.

    Academic text (2002)
  • Our observations with single-agent mitoxantrone are consistent with reports by other investigators.

    Academic text (2002)
  • Mitoxantrone is the only approved therapy in the USA for all these clinical forms of multiple sclerosis.

    Academic text (2002)
  • Encouraging results in open-label studies prompted this randomized trial of mitoxantrone in such patients.

    Academic text (2002)
  • We believe mitoxantrone provides a new therapeutic option for patients with worsening relapsing-remitting and secondary progressive multiple sclerosis.

    Academic text (2002)
  • Although decreases in left-ventricular ejection fraction were detected more frequently in mitoxantrone than in placebo groups, this difference was not significant.

    Academic text (2002)
  • The primary efficacy assessment was based on experience from the pilot trial with 12 mg/m² mitoxantrone.

    Academic text (2002)
  • The time to first treated relapse differed significantly between the placebo and 12 mg/m² mitoxantrone groups (p=0.0004, log-rank test).

    Academic text (2002)

Surface Forms

mitoxantrone singular
mitoxantrones plural

Etymology

Mitoxantrone is a modern drug name made of parts: mito-, which you can remember as 'mitosis' or 'cell division', and -xantrone, a chemical-like ending found in some cancer medicines. A helpful way to remember it is that mitoxantrone is a chemical that acts on cells, which is why it is used in chemotherapy and to treat multiple sclerosis.