mercaptopurine

Examples

• All

• When the FDA wanted to require a genetic test before administering 6-mercaptopurine to treat childhood leukemia, for instance, physicians' groups balked.

  Academic text (2006)

• There are no randomized trials to evaluate the efficacy of maintenance chemotherapy with 6-mercaptopurine and methotrexate in children with ALL who receive modern intensive chemotherapy.

  Academic text (1992)

• If maintenance chemotherapy with 6-mercaptopurine and methotrexate helps to cure ALL, how does it work?

  Academic text (1992)

• Smaller doses of 6-mercaptopurine and methotrexate began to be used instead for maintenance chemotherapy, typically given continuously over 2 to 3 years.

  Academic text (1992)

• There are several models of how maintenance chemotherapy with 6-mercaptopurine and methotrexate might prevent relapse.

  Academic text (1992)

• Maintenance treatment with low-dose 6-mercaptopurine and methotrexate continued to be used; 5-year

  Academic text (1992)

• For instance, testing can identify a minor genetic variation that predicts a toxic response to 6-mercaptopurine, a drug used to treat a form of childhood leukemia.

  Academic text (2006)

• Even regimens that give higher doses of 6-mercaptopurine and methotrexate are unlikely to kill leukemia stem cells without causing bone marrow aplasia.

  Academic text (1992)

• Doctors commonly prescribe mercaptopurine as part of the chemotherapy regimen for patients with acute lymphocytic leukemia.

• The oncologist explained that mercaptopurine works by interfering with purine metabolism to fight cancer cells.

Synonyms

P

Purinethol

vsmercaptopurine

• Specialized

9.8

A brand name drug used to treat a type of blood cancer called leukemia

is the generic name for the same drug rather than a brand

Surface Forms

Morphology

Etymology