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macrolide

macrolide

1 6.7
An antibiotic with a large ring of atoms used to treat bacterial infections
  • noun
  • /ˈmækroʊlaɪd/
  • Specialized
: macrólido
  • Many doctors prescribe macrolide antibiotics to patients who cannot take penicillin.
  • macrolide resistance
  • macrolide antibiotics

Examples

  • As a result, amoxicillin/clavulanic acid and newer macrolides have gained wider acceptance in recent years as potential first-line agents for acute sinusitis.

    Academic text (2003)
  • Taking azithromycin is contraindicated in patients allergic to macrolide antibiotics.

    Academic text (1995)
  • For 2 of these patients, treatment with macrolides during the month before sampling was reported.

    Academic text (2015)
  • Broad-spectrum cephalosporins were the most commonly prescribed agents in younger children, while macrolide antibiotics were more common in older children.

    Academic text (2005)
  • Macrolides and beta-lactam antibiotics have a favorable safety profile in pregnancy and provide adequate coverage for the most common organisms.

    Academic text (2007)
  • Because mycoplasmas, which do not have cell walls, are not susceptible to β-lactam antimicrobial drugs, macrolides are generally accepted as first-choice agents for treatment, especially in children.

    Academic text (2015)
  • Macrolide antibiotics, such as azithromycin, are effective in treating various bacterial infections.

  • Research shows that macrolides can be beneficial in treating respiratory tract infections caused by bacteria.

How Broad

ampicillin
  • Specialized
3 3.7
macrolide
  • Specialized
1 6.7
antibacterial drug
  • Specialized
1 3.0

Surface Forms

macrolide singular
macrolides plural

Morphology

macrolide = macro (semi-transparent) = macro + lide

The macro- element contributes the idea of largeness, but the remaining chemistry-specific ending and the specialized antibiotic sense are only partly recoverable for an average learner.

Etymology

The word macrolide comes from the Greek root macro- meaning 'large' and the chemical ending -ide. Macrolide antibiotics are called this because their molecules make a 'large' ring, and that ring is important for how they fight bacteria.