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isoenzyme

isoenzyme

1 8.1
A slightly different form of an enzyme that does the same job in the body
  • noun
  • /ˌaɪsoʊˈɛnzaɪm/
  • Specialized
: isoenzima
  • The different isoenzymes of alcohol dehydrogenase in the liver help process alcohol more efficiently.
  • isoenzyme of LDH
  • isoenzyme of alkaline phosphatase
  • isoenzyme patterns

Examples

  • In bovine brain, methionine adenosyltransferase is present as the gamma isoenzyme—the same form as is found in red cells.

    Academic text (1991)
  • Cardiac enzymes (creatine phosphokinase and its MB isoenzyme) were analyzed at study entry, 4 h, and 10 h.

    Academic text (2000)
  • The technique for making genetic profiles is isoenzyme electrophoresis.

    Academic text (1990)
  • Deficiency of the hepatic beta isoenzyme causes biochemical findings very similar to those in our patient C.

    Academic text (1991)
  • Neither microbial contamination nor cross-contamination was detected by isoenzyme analyses.

    Academic text (2013)
  • The present study on the LDH isoenzyme patterns of Angora goat fibroblasts showed that LDH-3 and LDH-4 were dominant.

    Academic text (2013)
  • We improved the apparatus and conditions for polyacrylamide gel electrophoresis to determine the mobility of the isoenzymes of LDH and MDH.

    Academic text (2013)
  • Elevations of the bone isoenzyme of alkaline phosphatase may further delineate Paget's disease as a diagnostic consideration (Pagana & Pagana, 2003).

    Academic text (2004)
  • In human blood, the lactate dehydrogenase enzyme exists as multiple isoenzymes that catalyze the same reaction.

  • Scientists have identified several isoenzymes of amylase that contribute to the digestion of starch in the human body.

Synonyms

isoform
vsisoenzyme
  • Specialized
2 9.1

A slightly different version of a protein made from the same gene that works in a similar way

is limited to reaction-catalyzing proteins that exist in multiple forms within a species
isozyme
vsisoenzyme
  • Specialized
1 9.9

An enzyme that does the same job as another enzyme but has a different shape

focuses on multiple forms within a species rather than structural difference

Surface Forms

isoenzyme singular
isoenzymes plural

Morphology

isoenzyme = enzyme (semi-transparent) = iso + enzyme + iso

The prefix 'iso-' indicates sameness, but the specific biochemical context may not be immediately clear to all learners.

Etymology

Isoenzyme comes from the prefix iso- meaning 'equal' and the familiar word enzyme meaning 'a substance that helps chemical reactions'. So an isoenzyme is one of several enzyme forms that do the 'same' job in the body.