imidazole
1
9.9
- noun
- /ˌɪmɪˈdæzoʊl/
- Specialized
- In 1978, Cosgrove et al. theorized that combining amphotericin B with an imidazole antifungal might result in antagonism because the two agents competed for the same binding sites on cell membranes.
Examples
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In the laboratory experiment, a precise amount of imidazole was required to obtain accurate results.
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Furthermore, imidazole rings of the His ligands should be located cis to each other.
Academic text (2001) -
Relationship between compound palatability in fish-feeding experiments and molecular structure for pyrrole-imidazole alkaloids from sponges of the genus Agelas.
Academic text (2011) -
The "medium" model used here replaces NH2 ligands with an imidazole ring, and H2O ligands with the C1 carboxylate ligands in the small model.
Academic text (2001) -
Metal M1 is coordinated by four carboxylate groups (Fig. 3), while metal M2 is coordinated by one imidazole and three carboxylate groups (Collyer et al., 1990).
Academic text (2015) -
The compound imidazole is often used as a base in the synthesis of various chemicals and pharmaceuticals.
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In biochemistry, imidazole plays a crucial role in enzyme catalysis and molecular biology.
Synonyms
A chemical used in medicine to reduce histamine in the body
Surface Forms
Etymology
Imidazole is built from parts that describe its shape and atoms: imid- (from 'imide', a nitrogen-containing group) and -azole (a name chemists use for a small ring with nitrogen). So imidazole is a small ring with nitrogen atoms, which helps explain why it appears in many medicines and biological molecules.