hydroxyproline

1 9.9

A building block of protein found in collagen that helps keep it strong

noun
/haɪˌdrɒk.siˈproʊ.laɪn/

Specialized

: hidroxiprolina

There is direct evidence of bone mineral and matrix resorption in urinary excretion studies of calcium, phosphorus, hydroxyproline, and other components (1, 3, 8, 9).

Bone broth contains proline, glycine, hydroxyproline, and glutamine.

Examples

The interpretation of hydroxyproline excretion in relation to body weight is further complicated by the changes in body composition; in soft tissues, the proportion of collagen to non-collagen protein increases substantially in malnutrition.

Academic text (1992)
A urine hydroxyproline.

Academic text (2006)
Bone broth contains proline, glycine, hydroxyproline, and glutamine.

Dr. Josh Axe
Your connective tissue needs proline, hydroxyproline, glycine, and lysine.
Hydroxyproline is an important component of hydroxyproline, helping to strengthen the structure of connective tissues.
Researchers found that higher levels of hydroxyproline in the samples indicated better collagen integrity.
Many gelatin products contain hydroxyproline, which is crucial for maintaining healthy skin and joints.

Surface Forms

hydroxyproline singular

hydroxyprolines plural

Morphology

hydroxyproline = proline (semi-transparent) = hydroxy + proline

Formation is regular (hydroxy- + proline) but 'hydroxy-' is a technical chemical combining form that many learners may not know, so understanding requires specialized knowledge.

Etymology

Hydroxyproline breaks into hydroxy- meaning 'with oxygen and hydrogen' and proline, an amino acid in proteins like collagen. So hydroxyproline is simply proline with a small extra 'hydroxy' part, and that change helps collagen stay strong.