fluorouracil
- noun
- /ˌflʊəroʊˈjʊərəˌsɪl/
- Specialized
- The first course of chemotherapy consisted of 5-fluorouracil and mitomycin.
- 5-fluorouracil
- fluorouracil infusion
Examples
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During her treatment, she received fluorouracil to help combat the effects of colon cancer.
-
During each of the three initial courses, the patient was admitted for five days to receive infusional chemotherapy with 5-fluorouracil and cisplatin combined with radiation therapy administered twice daily.
Academic text (1995) -
A 5-fluorouracil infusion was started at least 2 hours before the first radiation fraction.
Academic text (1999) -
The fluorouracil is converted by other enzymes and interferes with DNA synthesis.
Academic text (2005) -
Radiation therapy was used concomitantly with 5-fluorouracil and cisplatin.
Academic text (1995) -
Significant disadvantages in local failure, colostomy, and disease-free survival were seen in patients receiving 5-fluorouracil alone.
Academic text (1999) -
Sorafenib, 5-fluorouracil, and doxorubicin are currently the standard treatment for systemic or locoregional disease, but have limited efficacy.
Academic text (2017) -
This UKCCCR trial demonstrated that the addition of 5-fluorouracil and mitomycin to radical radiotherapy substantially improved the chance of avoiding local failure of anal cancer, and hence radical surgery and colostomy.
Academic text (1999) -
The doctor recommended using a cream that contains fluorouracil to treat the skin cancer.
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After being diagnosed with breast cancer, he was prescribed fluorouracil as part of his chemotherapy regimen.
Surface Forms
Morphology
Etymology
Fluorouracil comes from two parts: fluoro, from 'fluorine' and seen in fluoride, and uracil, a chemical found in cells' genetic material called RNA. So fluorouracil is basically uracil with fluorine added, and that change helps the drug slow or stop cancer cells from growing, which is why it is used to treat cancer.