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deamination

deamination

7.9
A process that removes an amino group from an amino acid in the body
  • noun
  • /ˌdiːəˈmɪneɪʃən/
  • Specialized
translation icon : desaminación
  • Deamination is a crucial step in the metabolism of amino acids, removing the amino group to facilitate further biochemical reactions.

Examples

  • There is some chemistry for example that will convert cytosine to uracil called a deamination mechanism.

  • The biological background of the mutational processes in diverse cancer types has been revealed by recent studies, such as APOBEC-induced deamination, deamination of methylated cytosine, tobacco and alcohol exposure, and so on 8-10.

    Academic text (2018)
  • If they see a uracil that can come from a deamination of the cytosine, so it gets taken out of the DNA, it shouldn't be in DNA.

  • Direct measurement of intracellular ammonium is technically difficult because of the possible deamination of amino acids during extraction and analysis.

    Academic text (1993)
  • Aside from this obvious example of cytosine deamination, the association between the context effects and their causative mutagenic processes is poor, limiting our ability to comment further.

    Blog text (25)
  • The biological background of the mutational processes in diverse cancer types has been revealed by recent studies, such as APOBEC-induced deamination, deamination of methylated cytosine, tobacco and alcohol exposure, and so on 8-10.

    Academic text (2018)
  • Deamination of C to U, and the reverse process (U → C amination), occur in several plant mitochondrial mRNA transcripts as well.

    Academic text (1996)
  • In cellular processes, the deamination of amino acids results in the production of ammonia, which is then detoxified by the liver.

  • The research findings highlighted that the rate of deamination in certain compounds may impact the efficiency of protein synthesis.

Synonyms

deaminization
vsdeamination
  • Specialized
9.9

Removing a small nitrogen part from a protein building block or similar chemical

is the standard scientific form used especially in metabolic contexts

Surface Forms

deamination singular
deaminations plural

Morphology

deamination = deaminate (semi-transparent) = de + amin + ate + ion

The noun is formed in a standard and fully predictable way from the verb 'deaminate' with the suffix '-ion'.

Etymology

Deamination comes from the parts de- meaning 'remove', amine meaning 'a nitrogen-containing part' as in amino acids, and -ation meaning 'the act of'. So, deamination is the 'act of removing an amino group', which is exactly what the term describes in metabolism.