deacetylation
- noun
- /ˌdiːəˌsɛtɪˈleɪʃən/
- Specialized
:
desacetilación
- Deacetylation is essential for regulating gene expression in many biological systems.
Examples
-
The process of deacetylation in histones can lead to increased transcription of certain genes.
-
In summary, epigenetic changes such as DNA methylation and/or histone deacetylation significantly contribute to SLeX/A overexpression, particularly during the early stages of disease 94.
Academic text (2016) -
As a side effect of deacetylation reactions, you usually also observe from the inhibition of mtor and the activation of AMP kinase.
-
The step in question, the KOH deacetylation reaction, is one of the end steps, and as NoR and another chemist friend remarked, the relative quantities in the protocol were grossly overkill.
Blog text (7) -
During deacetylation, the acetyl group is removed from the molecule, affecting its overall function.
How Acetylated
- Specialized
- Specialized
Surface Forms
Morphology
deacetylation = deacetylate (semi-transparent) = de + acetyl + ation
Formation from the verb 'deacetylate' plus the nominalizing suffix '-ation' is regular, but comprehension requires knowledge of the technical root 'acetyl'.
Etymology
Deacetylation is built from de- meaning 'remove', acetyl from the old word 'acetum' meaning 'vinegar' and seen in acetic as in 'acetic acid', and -ation meaning 'process'. So deacetylation means the process of 'removing' an 'acetyl' part from a molecule, which is why scientists use it for that chemical change.
