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cytotoxic T cell

cytotoxic T cell

5.5
A white blood cell with a CD8 marker that kills infected or cancer cells
  • noun
  • /ˌsaɪtəʊˈtɒksɪk tiː sɛl/
  • Specialized
translation icon : célula T citotóxica
  • Cytotoxic T cells play a crucial role in identifying and eliminating cells that are infected by viruses.

Examples

  • Now, in the lymph node, the cytotoxic T cells are activated.

  • These studies indicate that HBcAg can be a stimulus for both helper and cytotoxic T cells.

    Academic text (1994)
  • HLA-restricted cytotoxic T cells recognize viral peptides in association with class 1 HLA molecules on the target hepatocyte.

    Academic text (1994)
  • However, it is not clear how depletion of CD4+ lymphocytes would directly enhance hepatic fibrosis, which has been linked with a more vigorous cytotoxic T-cell response.

    Academic text (2002)
  • These cells act as effector cells, either directly (cytotoxic T cells) or by activating other effector cells such as antibody-secreting B cells or antigen-specific activated macrophages.

    Academic text (1991)
  • After vaccination, cytotoxic T cells become activated and seek out and destroy the infected cells.

  • Research shows that cytotoxic T cells are essential for the immune system to effectively fight off infections.

Synonyms

killer cell
vscytotoxic T cell
  • Specialized
1 4.3

A white blood cell that finds and kills virus-infected cells

is the scientific description stressing killing infected cells to protect the body
CD8 T cell
vscytotoxic T cell
  • Specialized
4.6

A kind of immune cell that finds and kills cells infected by viruses

is the broader concept emphasising body protection by killing infected cells
CD8 cell
vscytotoxic T cell
  • Specialized
5.5

A type of white blood cell that finds and kills virus-infected or abnormal cells

focuses on infected cells and defence rather than also treating abnormal cells
killer T cell
vscytotoxic T cell
  • Specialized
5.2

A white blood cell that finds and destroys virus-infected or cancerous body cells

focuses on removing infected cells to protect the body rather than cancer

Surface Forms

Morphology

cytotoxic + T + cell

The noun phrase is compositionally transparent: 'cytotoxic' means harmful to cells and 'T cell' denotes a class/type of cell, so a learner who knows the constituents can infer it is a type of cell that kills other cells. Detailed immunological specifics (e.g. CD8 receptor) are technical but not required to grasp the core meaning, making the MWE readily derivable from its parts.

Etymology

Cytotoxic T cell gets its name from its parts: cyto means 'cell' and toxic means 'poison', so the name points to a T cell that can damage other cells. That's why a cytotoxic T cell is a T cell that finds and 'kills' infected or cancerous cells to protect the body.