chromosomal abnormality
1
6.1
- noun
- /ˌkroʊməˈsoʊməl əbˈnɔːrməlɪti/
- Specialized
:
anomalía cromosómica
- Specifically, at age 35, a woman's risk of developing the chromosomal abnormality that causes Down syndrome dramatically increases.
- chromosomal abnormality caused
- risk of chromosomal abnormalities
- chromosomal abnormalities underlie
Examples
-
My DH and I both have no known chromosomal abnormalities that would lead to this, and I am only 31.
Blog text (25) -
Chromosomal abnormalities present a significantly different constellation of genetic factors.
Academic text (2005) -
We were interested in studying DNA chromosomal abnormalities.
Academic text (2017) -
No hereditary or chromosomal abnormality is reported in these cases.
Academic text (2015) -
Given the increased risk, particularly the risk of birth defects caused by chromosomal abnormalities, several additional tests are required for women age 35 or older.
Blog text (28) -
Patients with underlying chromosomal abnormalities or other craniofacial disorders were excluded.
Academic text (2015) -
Approximately 80% of couples achieve pregnancy within 12 months of trying, although fertility decreases and the risk of chromosomal abnormalities increases as women get older.
Academic text (2015) -
Spontaneous abortions occur in 1 out of 6 pregnancies; 60% of those have chromosomal abnormalities.
Academic text (2004) -
He also had another much rarer chromosomal abnormality—a partial duplication of another of his chromosomes.
Blog text (14) -
Two tests are currently available to detect chromosomal abnormalitys.
Synonyms
1
6.7
A change in the number or shape of chromosomes that often causes health problems
1
8.9
A change in the usual number or shape of chromosomes that often causes physical and mental problems
1
5.3
A health condition caused by a change in chromosomes that can affect the body or mind
Change in the number or shape of the parts in a cell that carry genes
How Severe
- Specialized
1
5.3
- Specialized
- Specialized
1
8.9
- Specialized
1
6.1
- Specialized
1
6.7
Surface Forms
Morphology
The phrase is directly compositional: 'chromosomal' means relating to chromosomes and 'abnormality' means a deviation from the norm, so a B1 learner who knows the constituents can infer it refers to an abnormality of chromosomes (changes in number or structure). Although it is technical vocabulary, the adjective+noun combination follows standard compositional patterns and similar constructions exist in many languages, making the meaning predictable from the parts.
Etymology
Chromosomal abnormality comes from thinking of chromosomes as tiny instruction books inside every cell. If a book has an 'extra', 'missing' or 'torn' page (a chromosomal change), the body's instructions change, so the term means a change in chromosomes that often causes health or development problems.