carbachol

1 8.6

A man-made medicine that makes nerves and muscles work to treat glaucoma and help the bladder and intestines

noun
/kɑrˈbɑːkɒl/

Specialized

: carbacol

Doctors often use carbachol to help treat patients with glaucoma by stimulating the muscles in the eye.

Examples

However, a study on isolated rabbit hearts found that muscarinic receptor stimulation through carbachol improved functional recovery in isolated hearts.

Academic text (2016)
Moreover, carbachol, a cholinergic agonist, is capable of inhibiting the secretion of testosterone via purified rat Leydig cells 9, 10.

Blog text (3)
Cholinergic stimulation with carbachol did not attenuate stunning.

Academic text (2016)
In fact, stunning was exacerbated significantly despite treatment with carbachol, indicating that decreasing cyclic AMP acutely may not be a useful strategy to protect the myocardium from ischemia.

Academic text (2016)
Thus, the difference between methacholine and acetylcholine probably relates to differential actions of the two agents on muscarinic receptor subtypes, as has been suggested to explain the differences in the actions of carbachol and acetylcholine on endothelium-dependent relaxation.

Academic text (1992)
To enhance intestinal motility during surgery, the anesthesiologist administered carbachol to the patient.
In clinical trials, carbachol has shown promise in stimulating the bladder to help patients with urinary retention.

Surface Forms

carbachol singular

carbachols plural

Etymology

Carbachol comes from two parts: carba- (from 'carbamoyl', a chemical group) and -chol (from 'choline', a natural nerve chemical). So, the name shows it is a man-made drug related to 'choline' that is used to make nerves and muscles work.