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bradykinin

bradykinin

8.8
A small protein that makes blood vessels widen and causes pain and swelling
  • noun
  • /ˌbrædɪˈkaɪnɪn/
  • Specialized
translation icon : bradicinina
  • Doctors study bradykinin for its effects on blood vessel dilation and its involvement in pain responses.
  • bradykinin and adrenomedullin
  • peptides, bradykinin

Examples

  • Unfortunately, treatment with omapatrilat inhibited not only ACE and neprilysin but also aminopeptidase P, which plays an important role in bradykinin degradation.

    Academic text (2016)
  • ACE also cleaves the vasodilator bradykinin, releasing an inactive 7-amino acid product.

    Academic text (2018)
  • Since heart failure is accompanied by resistance to some actions of bradykinin, angioedema might be less of a safety issue in this disorder.

    Academic text (2016)
  • Among them is bradykinin, a very potent activator of group III and IV afferent nerve endings, the afferents that signal pain to the CNS.

    Academic text (1997)
  • The peptide bradykinin is released during inflammation, causing blood vessels to widen and produce pain.

  • The role of bradykinin in the body includes signaling pain and inflammation during injury.

Surface Forms

bradykinin singular
bradykinins plural

Morphology

bradykinin = kinin (opaque) = brady + kinin

Formed from the medical combining form 'brady-' plus the technical biochemical noun 'kinin'; the parts are specialized and not derivable by an average B1 learner.

Etymology

Bradykinin comes from Greek parts brady- meaning 'slow' and kinin related to 'move', as in the familiar word kinetic. So a helpful way to remember bradykinin is to think of a 'slow-moving' body chemical that acts on blood vessels and can cause pain.