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atypia

atypia

1 9.9
An abnormal change in cells seen under a microscope that makes them look different from normal
  • noun
  • /eɪˈtɪpiə/
  • Specialized
translation icon : atipia
  • The pathologist noted the presence of atypia in the tissue sample, indicating potential abnormalities in the cells.
  • cellular atypia
  • cytologic atypia
  • nuclear atypia

Examples

  • The increased cellularity and atypia can resemble features of malignancy, and these lesions have been confused with fibrosarcomas and malignant schwannomas.

    Academic text (1996)
  • Nuclear atypia was usually moderate (47%) or mild (29%).

    Academic text (1995)
  • Nuclear atypia was also determined on a three-grade scale.

    Academic text (1995)
  • There were no nuclear atypia or mitotic activity present (Figure 2).

    Academic text (2007)
  • However, the lymphoma typically features cytologic atypia and monomorphic cells.

    Academic text (2009)
  • Some warts show epithelial atypia, and these contain new HPV types.

    Academic text (2000)
  • The immune system plays a central role in cancer both in vigilance for atypia and in the symptomatology of cancers.

    Academic text (2007)
  • Rhabdomyosarcoma frequently has areas of necrosis, mitotic figures, and nuclear atypia.

    Academic text (2004)
  • The presence of hypercellularity and atypia may lead to the misdiagnosis of these lesions as sarcomas.

    Academic text (2007)
  • Histologic analysis reveals giant cells around a fibrous stroma and some degree of cellular atypia.

    Academic text (2005)

Synonyms

dysplasia
vsatypia
  • Specialized
4 9.4

Unusual growth of cells or body parts that can cause health problems

focuses on visual cell differences rather than developmental structural change
atypicality
vsatypia
8.3

Being different from the usual type or pattern

applies specifically to cell appearance seen in medical examinations

Antonyms

13 3.5

A time when things are usual and happen as expected

1 6.1

How much something is like a usual example in a group

How Atypical

neoplasia
  • Specialized
1 9.4
atypia
  • Specialized
1 9.9
dysplasia
  • Specialized
4 9.4
normal
1.0

Surface Forms

atypia singular
atypias plural

Morphology

atypia = atypical (semi-transparent) = a + typ + ia

The adjective 'atypical' (a- + typical) is recognizable, but the medical suffix '-ia' is specialized and may be unfamiliar to general learners.

Etymology

The word atypia comes from Greek parts a- meaning 'not' and typ- meaning 'type' or 'form', the same root you see in typical. So atypia literally means 'not typical', which helps you remember it is used for cells that look different or abnormal in medical checks.