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antimetabolite

antimetabolite

9.5
A drug that stops cells from using a chemical they need to grow and is used to treat cancer
  • noun
  • /ˌæntɪˈmɛtəˌbɒlaɪt/
  • Specialized
translation icon : antimetabolito
  • The doctor prescribed an antimetabolite to help stop the rapid division of cancer cells in the patient's body.

Examples

  • Methotrexate is an antimetabolite antineoplastic agent that inhibits folate metabolism, thus interfering with DNA synthesis.

    Academic text (2012)
  • Methotrexate is an antimetabolite used to treat certain types of cancer by inhibiting cell growth.

  • You could be working up a case of cancer... ...with a truckload of antimetabolites in you.

  • Surgeons began to find success with purine antimetabolites and with antilymphocytic globulin, developed by an upstart ex-football player named John Najarian.

    Academic text (2001)
  • Research indicates that antimetabolites can be effective in targeting the metabolic processes of cancerous cells.

How Inhibitory

cytotoxic drug
  • Specialized
1 4.9
antimetabolite
  • Specialized
9.5
inhibitor
  • Specialized
46 6.0

Surface Forms

Morphology

antimetabolite = metabolite (opaque) = anti + metabol + ite

Adding anti- to metabolite is regular prefixation, but the biomedical base word is specialized and the resulting meaning is not easily recoverable for an average learner.

Etymology

The word antimetabolite comes from anti- meaning 'against' and metabolite, from metabolism, which is how the body 'changes food into energy' or other chemical parts. So an antimetabolite is a substance that works 'against' those chemical processes in cells, which is why doctors use it to stop fast-growing cancer cells.