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affibody

affibody

9.9
A small man-made protein that sticks to a specific molecule and helps in medicine and research
  • noun
  • Specialized
: afibodía
  • The new affibody binds specifically to the receptor, allowing for precise delivery of medication.
  • affibody molecule
  • affibody tracer
  • specific affibody

Examples

  • However, the small size and lack of disulfide bridges also make affibody molecules interesting alternatives for intracellular targets.

    Academic text (2017)
  • Directed prodrug therapy has been explored using affibody molecules to deliver enzymes to tumor cells in vitro.

    Academic text (2017)
  • Recently, efforts to evaluate targeting affibody molecules for therapy applications have been performed.

    Academic text (2017)
  • Due to their simple structure, will it be possible to use de novo design to generate affibody molecules to desired targets?

    Academic text (2017)
  • Moreover, no adverse effects attributed to the affibody tracer were observed.

    Academic text (2017)
  • Using different variants of this affibody-targeted system, the authors demonstrated specific cell killing activity of HER2-positive cell lines in vitro.

    Academic text (2017)
  • In an even more complex study, an affibody-based trimodality nanoprobe was developed for combined PET, optical, and MRI.

    Academic text (2017)
  • Will FcRn-specific affibody molecules be more suitable compared with other serum half-life extension techniques for some disease indications?

    Academic text (2017)
  • Decreased uptake of radioactivity in kidneys compared with direct targeting with a radiolabeled affibody molecule was observed.

    Academic text (2017)
  • A first-generation anti-HER3 affibody molecule was shown to compete with the binding of the natural ligand, heregulin 59.

    Academic text (2017)

Surface Forms

affibody singular
affibodies plural

Etymology

Affibody is a modern mix of the words affinity ('a natural liking or attraction') and antibody ('a protein that binds germs'). So an affibody is a tiny engineered protein made to 'like' and stick to one specific molecule, which is why scientists use it to find targets or deliver medicines to particular cells.