affibody
- noun
- Specialized
- The new affibody binds specifically to the receptor, allowing for precise delivery of medication.
- affibody molecule
- affibody tracer
- specific affibody
Examples
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However, the small size and lack of disulfide bridges also make affibody molecules interesting alternatives for intracellular targets.
Academic text (2017) -
Directed prodrug therapy has been explored using affibody molecules to deliver enzymes to tumor cells in vitro.
Academic text (2017) -
Recently, efforts to evaluate targeting affibody molecules for therapy applications have been performed.
Academic text (2017) -
Due to their simple structure, will it be possible to use de novo design to generate affibody molecules to desired targets?
Academic text (2017) -
Moreover, no adverse effects attributed to the affibody tracer were observed.
Academic text (2017) -
Using different variants of this affibody-targeted system, the authors demonstrated specific cell killing activity of HER2-positive cell lines in vitro.
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In an even more complex study, an affibody-based trimodality nanoprobe was developed for combined PET, optical, and MRI.
Academic text (2017) -
Will FcRn-specific affibody molecules be more suitable compared with other serum half-life extension techniques for some disease indications?
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Decreased uptake of radioactivity in kidneys compared with direct targeting with a radiolabeled affibody molecule was observed.
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A first-generation anti-HER3 affibody molecule was shown to compete with the binding of the natural ligand, heregulin 59.
Academic text (2017)
Surface Forms
Etymology
Affibody is a modern mix of the words affinity ('a natural liking or attraction') and antibody ('a protein that binds germs'). So an affibody is a tiny engineered protein made to 'like' and stick to one specific molecule, which is why scientists use it to find targets or deliver medicines to particular cells.