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actinomycin

actinomycin

1 9.5
A red antibiotic made by soil bacteria and used in research and cancer treatment
  • noun
  • /ˌæktɪˈnoʊmaɪsɪn/
  • Specialized
: actinomicina
  • We started treatment with our high-risk chemotherapy protocol, alternating etoposide, methotrexate, and actinomycin D every week with vincristine and cyclophosphamide, and heparin for anticoagulation.
  • actinomycin D

Examples

  • Melphalan (7.5 mL/L of tissue to be infused) with or without actinomycin-D (75/L) without adjustment for ideal body weight was used.

    Academic text (2015)
  • The oncologist prescribed actinomycin as part of the patient's chemotherapy regimen.

  • For example, chemotherapy was changed from melphalan with actinomycin-D to melphalan alone based on a lack of evidence for the additional actinomycin-D, and infusion time was reduced from 30 min to 15 min based on early complications.

    Academic text (2015)
  • For example, chemotherapy was changed from melphalan with actinomycin-D to melphalan alone based on a lack of evidence for the additional actinomycin-D, and infusion time was reduced from 30 min to 15 min based on early complications.

    Academic text (2015)
  • Researchers used actinomycin in the lab to study its effects on cancer cells.

  • In her studies, she discovered that actinomycin could inhibit the growth of certain bacteria.

Surface Forms

actinomycin singular
actinomycins plural

Morphology

actinomycin = actinomyces (opaque) = actinomyces + in

Formed from the bacterial name Actinomyces plus the chemical substance suffix '-in' (or antibiotic-forming suffix '-mycin'); this is a technical nomenclature not semantically transparent to general learners.

Etymology

The word actinomycin comes from the parts actino- and -mycin, where actino- means 'ray' and -mycin comes from a word for 'fungus'. This name describes the soil bacteria that make the red antibiotic — they grow as ray-like threads like a fungus, and the -mycin ending is used for many antibiotics, so actinomycin is an antibiotic made by those 'ray' bacteria.