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trypsin

trypsin

1 8.2
A protein made in the pancreas that helps break down food proteins in the small intestine
  • noun
  • /ˈtrɪpsɪn/
  • Specialized
translation icon : tripsina
  • The pancreas produces trypsin, which is essential for proper protein digestion.
  • trypsin inhibitor

Now remember, we're told that our peptide, this mystery protein, it actually comes as a result of a trypsin digest.

Examples

  • The proteins are then digested to peptides with trypsin or other proteolytic enzymes and analyzed using standard proteomics.

    Academic text (2016)
  • The neurons were dissociated with collagenase type IV (Sigma) and 0.1% trypsin (Worthington) and centrifuged through a 15% BSA density.

    Academic text (2016)
  • After 48 hours of incubation, the medium of each group was removed and the cells were detached using Trypsin-EDTA.

    Academic text (2018)
  • At the third passage, UCMSCs were digested by 0.25% trypsin.

    Academic text (2018)
  • Cultures were transferred by means of trypsin (0.25%) and 5 mmol/l edetic acid (EDTA).

    Academic text (1992)
  • At 80% confluence, cell harvesting was carried out using 0.25% (w/v) trypsin-EDTA (Gibco), followed by centrifugation at 300g for 5 minutes.

    Academic text (2018)
  • During digestion, trypsin helps break down proteins into smaller peptides.

  • In the laboratory, scientists use trypsin to analyze protein structures effectively.

Surface Forms

trypsin singular
trypsins plural

Morphology

trypsin = tryps + in

The combining form 'tryps-' is not a standalone English word and the protein suffix '-in' is a technical biomedical marker, so an average B1 learner cannot derive the meaning from the parts.

Etymology

The word trypsin comes from the Greek root tryp- meaning 'to rub' and the common protein ending -in, so it was named for how the enzyme rubs or wears proteins apart during digestion.