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tamoxifen

tamoxifen

23 6.3
A drug that blocks the hormone estrogen to treat and prevent breast cancer
  • noun
  • /təˈmɒksɪfɛn/
  • Specialized
translation icon : tamoxifeno
  • Long-term follow-up of IBIS-I has shown that women at high risk for breast cancer continue to benefit from tamoxifen chemoprevention, with reductions in invasive breast cancer greater than 10 years after treatment.
  • tamoxifen therapy
  • tamoxifen and chemotherapy
  • effect of tamoxifen

Secondly, it's tamoxifen, which is an estrogen receptor blocker.

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Examples

  • Secondly, it's tamoxifen, which is an estrogen receptor blocker.

  • Despite the impressive evidence for benefits with tamoxifen, uptake of breast cancer chemoprevention is low (2).

    Academic text (2015)
  • Of the trials involving women currently taking tamoxifen, there are two main trial structures.

    Blog text (13)
  • Only a smaller trial suggested a possible benefit from increasing the length of adjuvant tamoxifen treatment.

    Blog text (13)
  • In women at increased risk for breast cancer, does 5 years of tamoxifen therapy reduce long-term risk for breast cancer?

    Academic text (2015)
  • Tamoxifen vs. placebo for 5 years in women at increased risk for breast cancer.

    Academic text (2015)
  • Pre-menopausal women with hormone receptor-positive early breast cancer may be prescribed tamoxifen, a selective oestrogen receptor modulator.

    Academic text (2012)
  • Tamoxifen is commonly prescribed to women after surgery to prevent the recurrence of breast cancer.

  • Research shows that tamoxifen can significantly reduce the risk of developing breast cancer in at-risk women.

  • For patients diagnosed with hormone receptor-positive breast cancer, tamoxifen serves as an effective treatment option.

Synonyms

estrogen antagonist
vstamoxifen
  • Specialized
6.7

A medicine that stops estrogen from working used to treat some breast cancers

is a single specific medication rather than the general drug class

Surface Forms

tamoxifen singular
tamoxifens plural

Etymology

Tamoxifen is a modern drug name made from parts of chemical words, so a helpful way to remember it is to see tamox as the family label and the ending -ifen as a medicine ending. It acts as an anti-estrogen, meaning 'against' the hormone estrogen, so tamoxifen is used to treat and prevent breast cancer.