reporter
6
8.1
- noun
- /rɪˈpɔrtər/
- Specialized
:
gen reportero
- So early on in my lab, we developed a mouse model where we can tag the heart muscles with a reporter that glows green when the heart muscle cell is formed.
- luciferase reporter
- COX-2 reporter
- reporter gene
We've basically developed this technology for massively parallel reporter assays MPRA.
- We've basically developed this technology for massively parallel reporter assays MPRA.
Examples
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Now we take it all for granted, but GFP can be used as a a reporter gene to do a number of things in in cellular systems.
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The Beclin 1 reporter mice and hAPP-transgenic mice were bred on a C57BL/6 genetic background.
Academic text (2018) -
So in this approach, you have a reporter gene that normally is not going to be transcribed.
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Beclin 1 was cloned into third-generation lentiviral plasmids with and without an IRES eGFP reporter.
Academic text (2018) -
To measure and visualize autophagic flux, the LC3-GFP reporter construct was cloned into a third-generation lentiviral vector.
Academic text (2018) -
The PCR products were cloned into the pMiR-luc luciferase reporter vector (Ambion, Grand Island, NY, USA).
Academic text (2014) -
In our experiment, the reporter gene produces a bright signal, indicating gene activity.
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The research team used a reporter construct that emits fluorescence to track gene expression.
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When activated, the reporter provided clear evidence of the genetic changes in the cells.
Compounds
How Detectable
Surface Forms
Morphology
Etymology
Reporter in biology comes from the same word report, built from old Latin parts re- 'back' and portare 'to carry'. A reporter gene 'carries' a clear signal that shows when another gene is active, just like a news reporter brings information.