pyrogen
1
9.9
- noun
- /ˈpaɪrəˌdʒɛn/
- Specialized
:
pirógeno
- Certain substances are classified as pyrogens because they induce fever when introduced into the bloodstream.
Examples
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U.S. Food and Drug Administration issues guidance document on pyrogen and endotoxins testing.
Blog text (24) -
For the collection of endotoxin, each impinger contained 20 ml of pyrogen-free water.
Academic text (2004) -
The chemicals your immune system uses are literally called pyrogens, meaning they heat up the body to burn out the invading.
Blog text (15) -
Firms producing products for which pyrogen testing is required may use alternative methods if they provide advantages in terms of accuracy, sensitivity, precision, selectivity, or adaptability to automation or computerized data reduction, and in other special circumstances.
Blog text (24) -
These authors suggested that the P2X7R plays a central role, which is perhaps unsurprising given that the cytokines IL-6, IL-1, and TNF- all act as endogenous pyrogens.
Blog text (33) -
When bacteria enter the body, they can release pyrogen that raises body temperature and causes fever.
-
In response to infection, the immune system produces pyrogens that trigger an increase in body temperature.
Synonyms
A substance that makes the body temperature rise
Antonyms
Surface Forms
Morphology
pyrogen = pyro + gen
The word is built from scientific combining forms meaning roughly 'fire/fever' and 'producing', but the medical sense 'fever-causing substance' is specialized and not readily inferable for an average learner.
Etymology
Pyrogen combines pyro- 'fire' and -gen, like in generate, 'to make'. So a pyrogen is literally something that 'makes fire', which helps you remember it as a substance that makes the body heat up or causes a fever.